2lz1
From Proteopedia
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==Solution NMR Structure of the DNA-Binding Domain of Human NF-E2-Related Factor 2, Northeast Structural Genomics Consortium (NESG) Target HR3520O== | ==Solution NMR Structure of the DNA-Binding Domain of Human NF-E2-Related Factor 2, Northeast Structural Genomics Consortium (NESG) Target HR3520O== | ||
| - | <StructureSection load='2lz1' size='340' side='right'caption='[[2lz1 | + | <StructureSection load='2lz1' size='340' side='right'caption='[[2lz1]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lz1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2lz1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LZ1 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lz1 OCA], [https://pdbe.org/2lz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lz1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lz1 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lz1 OCA], [https://pdbe.org/2lz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lz1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lz1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/NF2L2_HUMAN NF2L2_HUMAN] Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.<ref>PMID:11035812</ref> | |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Acton | + | [[Category: Acton TB]] |
| - | [[Category: Eletsky | + | [[Category: Eletsky A]] |
| - | [[Category: Everett | + | [[Category: Everett JK]] |
| - | [[Category: Janjua | + | [[Category: Janjua H]] |
| - | [[Category: Kohan | + | [[Category: Kohan E]] |
| - | [[Category: Lee | + | [[Category: Lee D]] |
| - | [[Category: Montelione | + | [[Category: Montelione GT]] |
| - | + | [[Category: Pulavarti SVSRK]] | |
| - | [[Category: Pulavarti | + | [[Category: Szyperski T]] |
| - | [[Category: Szyperski | + | [[Category: Xiao R]] |
| - | [[Category: Xiao | + | |
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Current revision
Solution NMR Structure of the DNA-Binding Domain of Human NF-E2-Related Factor 2, Northeast Structural Genomics Consortium (NESG) Target HR3520O
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Categories: Homo sapiens | Large Structures | Acton TB | Eletsky A | Everett JK | Janjua H | Kohan E | Lee D | Montelione GT | Pulavarti SVSRK | Szyperski T | Xiao R
