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7mx2
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7mx2 is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human ternary NatC complex with a Bisubstrate inhibitor== | |
| - | + | <StructureSection load='7mx2' size='340' side='right'caption='[[7mx2]], [[Resolution|resolution]] 3.64Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7mx2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MX2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.64Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMC:CARBOXYMETHYL+COENZYME+*A'>CMC</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mx2 OCA], [https://pdbe.org/7mx2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mx2 RCSB], [https://www.ebi.ac.uk/pdbsum/7mx2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mx2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NAA35_HUMAN NAA35_HUMAN] Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.<ref>PMID:19398576</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Deng S]] | ||
| + | [[Category: Marmorstein R]] | ||
Current revision
Cryo-EM structure of human ternary NatC complex with a Bisubstrate inhibitor
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