7o7k
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the human DYRK1A kinase domain bound to abemaciclib== | |
| - | + | <StructureSection load='7o7k' size='340' side='right'caption='[[7o7k]], [[Resolution|resolution]] 1.82Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O7K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6ZV:N-{5-[(4-ETHYLPIPERAZIN-1-YL)METHYL]PYRIDIN-2-YL}-5-FLUORO-4-[4-FLUORO-2-METHYL-1-(PROPAN-2-YL)-1H-BENZIMIDAZOL-6-YL]PYRIMIDIN-2-AMINE'>6ZV</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=LI:LITHIUM+ION'>LI</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o7k OCA], [https://pdbe.org/7o7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o7k RCSB], [https://www.ebi.ac.uk/pdbsum/7o7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o7k ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Anand K]] | ||
| + | [[Category: Geyer M]] | ||
| + | [[Category: Kaltheuner IH]] | ||
Current revision
Crystal structure of the human DYRK1A kinase domain bound to abemaciclib
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