This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2j08

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:30, 13 December 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='2j08' size='340' side='right'caption='[[2j08]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
<StructureSection load='2j08' size='340' side='right'caption='[[2j08]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2j08]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J08 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2j08]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J08 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=IRF:1-DEOXY-1-(8-IODO-7-METHYL-2,4-DIOXO-3,4-DIHYDROBENZO[G]PTERIDIN-10(2H)-YL)-D-RIBITOL'>IRF</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1iqr|1iqr]], [[1iqu|1iqu]], [[2cgb|2cgb]], [[2cgc|2cgc]], [[2j07|2j07]], [[2j09|2j09]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=IRF:1-DEOXY-1-(8-IODO-7-METHYL-2,4-DIOXO-3,4-DIHYDROBENZO[G]PTERIDIN-10(2H)-YL)-D-RIBITOL'>IRF</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Deoxyribodipyrimidine_photo-lyase Deoxyribodipyrimidine photo-lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.99.3 4.1.99.3] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j08 OCA], [https://pdbe.org/2j08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j08 RCSB], [https://www.ebi.ac.uk/pdbsum/2j08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j08 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j08 OCA], [https://pdbe.org/2j08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j08 RCSB], [https://www.ebi.ac.uk/pdbsum/2j08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j08 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/PHR_THET8 PHR_THET8]] Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation (By similarity).
+
[https://www.uniprot.org/uniprot/PHR_THET8 PHR_THET8] Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 34: Line 33:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Deoxyribodipyrimidine photo-lyase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Thet8]]
+
[[Category: Thermus thermophilus HB8]]
-
[[Category: Batschauer, A]]
+
[[Category: Batschauer A]]
-
[[Category: Carell, T]]
+
[[Category: Carell T]]
-
[[Category: Essen, L O]]
+
[[Category: Essen L-O]]
-
[[Category: Hennecke, U]]
+
[[Category: Hennecke U]]
-
[[Category: Kaiser, G]]
+
[[Category: Kaiser G]]
-
[[Category: Klar, T]]
+
[[Category: Klar T]]
-
[[Category: Dna repair]]
+
-
[[Category: Flavoprotein]]
+
-
[[Category: Lyase]]
+

Current revision

Thermus DNA photolyase with 8-Iod-riboflavin antenna chromophore

PDB ID 2j08

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2j08"
Personal tools