2mf2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:04, 15 May 2024) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Structural and biophysical characterization of the mRNA interferase SaMazF from Staphylococcus aureus.==
==Structural and biophysical characterization of the mRNA interferase SaMazF from Staphylococcus aureus.==
-
<StructureSection load='2mf2' size='340' side='right'caption='[[2mf2]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='2mf2' size='340' side='right'caption='[[2mf2]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2mf2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MF2 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2mf2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MF2 FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4mzm|4mzm]], [[4mzt|4mzt]], [[4mzp|4mzp]]</div></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mazF, MW1992 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mf2 OCA], [https://pdbe.org/2mf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mf2 RCSB], [https://www.ebi.ac.uk/pdbsum/2mf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mf2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mf2 OCA], [https://pdbe.org/2mf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mf2 RCSB], [https://www.ebi.ac.uk/pdbsum/2mf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mf2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/MAZF_STAAW MAZF_STAAW]] Toxic component of a toxin-antitoxin (TA) module. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. Cleavages occur preferentially in a U-rich region with a consensus sequence of 5'-[ACG]UU[ACG]-3' in single-stranded RNA (By similarity).
+
[https://www.uniprot.org/uniprot/MAZF_STAA8 MAZF_STAA8] Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA. Neutralized by coexpression with cognate antitoxin MazE.[UniProtKB:A6QIR4]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 24: Line 23:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Cheung, A]]
+
[[Category: Staphylococcus aureus]]
-
[[Category: Loris, R]]
+
[[Category: Cheung A]]
-
[[Category: Nuland, N A.J van]]
+
[[Category: Loris R]]
-
[[Category: Zorzini, V]]
+
[[Category: Zorzini V]]
-
[[Category: Ccdb/mazf fold]]
+
[[Category: Van Nuland NAJ]]
-
[[Category: Hydrolase]]
+
-
[[Category: Ribonuclease]]
+

Current revision

Structural and biophysical characterization of the mRNA interferase SaMazF from Staphylococcus aureus.

PDB ID 2mf2

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2mf2"
Personal tools