CD23
From Proteopedia
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| - | <StructureSection load='4gko' size='340' side='right' caption='Human CD23 (magenta/blue) with IgE (pink/yellow) and Ca+2 | + | <StructureSection load='4gko' size='340' side='right' caption='Human CD23 (magenta/blue) with IgE (pink/yellow) and Ca+2 ions (green) [[4gko]]' scene='77/776386/Cv/1'> |
== Function == | == Function == | ||
| - | '''CD23''' or '''low affinity immunoglobulin epsilon Fc receptor''' or '''Fc fragment of IgE receptor II''' is a low affinity receptor of IgE and serves as an adhesion molecule involved in cell-cell interaction<ref>PMID:9651788</ref>. | + | '''CD23''' or '''low affinity immunoglobulin epsilon Fc receptor''' or '''Fc fragment of IgE receptor II''' is a low affinity receptor of IgE and serves as an adhesion molecule involved in cell-cell interaction<ref>PMID:9651788</ref>. <scene name='77/776386/Cv/3'>Human CD23 with IgE and Ca+2 ions</scene> ([[4gko]]). |
== Disease == | == Disease == | ||
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[[2h2r]], [[4g96]], [[4g9a]], [[4j6j]], [[4j6k]], [[4j6l]], [[4j6m]], [[4j6n]], [[4j6p]], [[4j6q]] – hCD23 lectin domain 156-298 – human <br /> | [[2h2r]], [[4g96]], [[4g9a]], [[4j6j]], [[4j6k]], [[4j6l]], [[4j6m]], [[4j6n]], [[4j6p]], [[4j6q]] – hCD23 lectin domain 156-298 – human <br /> | ||
[[1t8c]], [[1t8d]] – hCD23 lectin domain – NMR<br /> | [[1t8c]], [[1t8d]] – hCD23 lectin domain – NMR<br /> | ||
| - | [[2h2t]], [[4gi0]], [[4gj0]], [[4gjx]], [[4gk1]] – hCD23 lectin domain (mutant)<br /> | + | [[2h2t]], [[4gi0]], [[4gj0]], [[4gjx]], [[4gk1]], [[6y0l]], [[6y0m]] – hCD23 lectin domain (mutant)<br /> |
[[4gko]], [[4ki1]], [[4ezm]] – hCD23 lectin domain + IgE-Fc<br /> | [[4gko]], [[4ki1]], [[4ezm]] – hCD23 lectin domain + IgE-Fc<br /> | ||
[[6pwr]], [[6pws]], [[6pwt]] – CD23 lectin domain - bovine<br /> | [[6pwr]], [[6pws]], [[6pwt]] – CD23 lectin domain - bovine<br /> | ||
Current revision
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3D Structures of CD23
Updated on 20-January-2025
2h2r, 4g96, 4g9a, 4j6j, 4j6k, 4j6l, 4j6m, 4j6n, 4j6p, 4j6q – hCD23 lectin domain 156-298 – human
1t8c, 1t8d – hCD23 lectin domain – NMR
2h2t, 4gi0, 4gj0, 4gjx, 4gk1, 6y0l, 6y0m – hCD23 lectin domain (mutant)
4gko, 4ki1, 4ezm – hCD23 lectin domain + IgE-Fc
6pwr, 6pws, 6pwt – CD23 lectin domain - bovine
References
- ↑ Bonnefoy JY, Lecoanet-Henchoz S, Gauchat JF, Graber P, Aubry JP, Jeannin P, Plater-Zyberk C. Structure and functions of CD23. Int Rev Immunol. 1997;16(1-2):113-28. doi: 10.3109/08830189709045705. PMID:9651788 doi:http://dx.doi.org/10.3109/08830189709045705
- ↑ Sarfati M. CD23 and chronic lymphocytic leukemia. Blood Cells. 1993;19(3):591-6; discussion 597-9. PMID:8018941
- ↑ DiRaimondo F, Albitar M, Huh Y, O'Brien S, Montillo M, Tedeschi A, Kantarjian H, Lerner S, Giustolisi R, Keating M. The clinical and diagnostic relevance of CD23 expression in the chronic lymphoproliferative disease. Cancer. 2002 Mar 15;94(6):1721-30. PMID:11920534
