We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

6t98

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:50, 7 February 2024) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
-
==Trypanothione Reductase from Leishmania infantum in complex with TRL187==
+
==Trypanothione Reductase from Leishmania infantum in complex with 9a==
<StructureSection load='6t98' size='340' side='right'caption='[[6t98]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='6t98' size='340' side='right'caption='[[6t98]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6t98]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leiin Leiin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T98 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T98 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6t98]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_infantum Leishmania infantum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T98 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T98 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MWZ:4-[3-methyl-1-[4-[4-(2-phenylethyl)-1,3-thiazol-2-yl]-3-(2-piperidin-4-ylethoxy)phenyl]-1,2,3-triazol-3-ium-4-yl]butan-1-amine'>MWZ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6t95|6t95]], [[6t97|6t97]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MWZ:4-[3-methyl-1-[4-[4-(2-phenylethyl)-1,3-thiazol-2-yl]-3-(2-piperidin-4-ylethoxy)phenyl]-1,2,3-triazol-3-ium-4-yl]butan-1-amine'>MWZ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRYR, LINF_050008500, LINJ_05_0350 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5671 LEIIN])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Trypanothione-disulfide_reductase Trypanothione-disulfide reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.12 1.8.1.12] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t98 OCA], [https://pdbe.org/6t98 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t98 RCSB], [https://www.ebi.ac.uk/pdbsum/6t98 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t98 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t98 OCA], [https://pdbe.org/6t98 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t98 RCSB], [https://www.ebi.ac.uk/pdbsum/6t98 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t98 ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/A4HSF7_LEIIN A4HSF7_LEIIN]
==See Also==
==See Also==
Line 16: Line 16:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Leiin]]
+
[[Category: Leishmania infantum]]
-
[[Category: Trypanothione-disulfide reductase]]
+
[[Category: Carriles AA]]
-
[[Category: Carriles, A]]
+
[[Category: Hermoso JA]]
-
[[Category: Hermoso, J A]]
+
-
[[Category: Complex]]
+
-
[[Category: Drug]]
+
-
[[Category: Flavoprotein]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Leishmania]]
+
-
[[Category: Oxidoreductase]]
+

Current revision

Trypanothione Reductase from Leishmania infantum in complex with 9a

PDB ID 6t98

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools