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2mit
From Proteopedia
(Difference between revisions)
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==Solution structure of oxidized dimeric form of human defensin 5== | ==Solution structure of oxidized dimeric form of human defensin 5== | ||
| - | <StructureSection load='2mit' size='340' side='right'caption='[[2mit | + | <StructureSection load='2mit' size='340' side='right'caption='[[2mit]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2mit]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2mit]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MIT FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mit OCA], [https://pdbe.org/2mit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mit RCSB], [https://www.ebi.ac.uk/pdbsum/2mit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mit ProSAT]</span></td></tr> |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mit OCA], [https://pdbe.org/2mit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mit RCSB], [https://www.ebi.ac.uk/pdbsum/2mit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mit ProSAT]</span></td></tr> | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/DEF5_HUMAN DEF5_HUMAN] Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.<ref>PMID:12021776</ref> <ref>PMID:15616305</ref> <ref>PMID:17088326</ref> | |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Nolan | + | [[Category: Nolan EM]] |
| - | [[Category: Wagner | + | [[Category: Wagner G]] |
| - | [[Category: Wommack | + | [[Category: Wommack AJ]] |
| - | [[Category: Ziarek | + | [[Category: Ziarek JJ]] |
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Current revision
Solution structure of oxidized dimeric form of human defensin 5
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