This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6p4e
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
==Leishmania mexicana CPB in complex with an aza-nitrile inhibitor== | ==Leishmania mexicana CPB in complex with an aza-nitrile inhibitor== | ||
| - | <StructureSection load='6p4e' size='340' side='right'caption='[[6p4e]]' scene=''> | + | <StructureSection load='6p4e' size='340' side='right'caption='[[6p4e]], [[Resolution|resolution]] 1.35Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6P4E FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6p4e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6P4E FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6p4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p4e OCA], [https://pdbe.org/6p4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6p4e RCSB], [https://www.ebi.ac.uk/pdbsum/6p4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6p4e ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GES:3-tert-butyl-N-[(2S)-1-(2-cyano-1,2-dimethylhydrazinyl)-4-methyl-1-oxopentan-2-yl]-1-methyl-1H-pyrazole-5-carboxamide+(non-preferred+name)'>GES</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6p4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p4e OCA], [https://pdbe.org/6p4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6p4e RCSB], [https://www.ebi.ac.uk/pdbsum/6p4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6p4e ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LMCPB_LEIME LMCPB_LEIME] | ||
==See Also== | ==See Also== | ||
| - | *[[Proteinase|Proteinase]] | + | *[[Proteinase 3D structures|Proteinase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Leishmania mexicana]] |
| + | [[Category: De Vita D]] | ||
| + | [[Category: Emsley J]] | ||
| + | [[Category: Li C]] | ||
| + | [[Category: Montanari CA]] | ||
| + | [[Category: Ribeiro JFR]] | ||
Current revision
Leishmania mexicana CPB in complex with an aza-nitrile inhibitor
| |||||||||||
