This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7oqv
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7oqv is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the polymerising VEL domain of VIN3 (I575D mutant)== | |
| - | + | <StructureSection load='7oqv' size='340' side='right'caption='[[7oqv]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7oqv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OQV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OQV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oqv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oqv OCA], [https://pdbe.org/7oqv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oqv RCSB], [https://www.ebi.ac.uk/pdbsum/7oqv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oqv ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VIN3_ARATH VIN3_ARATH] Plays a central role in vernalization by mediating the initial transcriptional repression of the homeotic gene FLC, a floral repressor, after a cold treatment. However, due to its transient expression, it cannot maintain repression of FLC, which is then maintained by Polycomb Group complexes containing VRN2 throughout development. Required to deacetylate histones on the FLC promoter. Together with VIL1, required during vernalization for the modifications of FLC and FLM chromatin that are associated with an epigenetically silenced state (e.g. chromatin modifications, histone deacetylation, and trimethylated H3 'Lys-4' H3K4me3 and 'Lys-27' H3K27me3) and with acquisition of competence to flower.<ref>PMID:14712276</ref> <ref>PMID:17114575</ref> <ref>PMID:17174094</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arabidopsis thaliana]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bienz M]] | ||
| + | [[Category: Dean C]] | ||
| + | [[Category: Fiedler M]] | ||
| + | [[Category: Franco-Echevarria E]] | ||
Current revision
Crystal structure of the polymerising VEL domain of VIN3 (I575D mutant)
| |||||||||||
