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7kb1
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==Complex of O-acety-L-homoserine aminocarboxypropyltransferase (MetY) from Thermotoga maritima and a key reaction intermediate== | ==Complex of O-acety-L-homoserine aminocarboxypropyltransferase (MetY) from Thermotoga maritima and a key reaction intermediate== | ||
| - | <StructureSection load='7kb1' size='340' side='right'caption='[[7kb1]]' scene=''> | + | <StructureSection load='7kb1' size='340' side='right'caption='[[7kb1]], [[Resolution|resolution]] 1.85Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KB1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KB1 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7kb1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KB1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KB1 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kb1 OCA], [https://pdbe.org/7kb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kb1 RCSB], [https://www.ebi.ac.uk/pdbsum/7kb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kb1 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=WBJ:(2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic+acid'>WBJ</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kb1 OCA], [https://pdbe.org/7kb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kb1 RCSB], [https://www.ebi.ac.uk/pdbsum/7kb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kb1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/METY_THEMA METY_THEMA] Catalyzes the production of homocysteine from O-acetylhomoserine (OAH) and hydrogen sulfide (H2S), a step in the methionine biosynthesis pathway. Is not able to form cystathionine from O-acetylhomoserine and L-cysteine.<ref>PMID:28640457</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Thermotoga maritima MSB8]] | ||
[[Category: Brewster JL]] | [[Category: Brewster JL]] | ||
[[Category: Pachl P]] | [[Category: Pachl P]] | ||
Current revision
Complex of O-acety-L-homoserine aminocarboxypropyltransferase (MetY) from Thermotoga maritima and a key reaction intermediate
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