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6m0t

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Current revision (15:08, 29 November 2023) (edit) (undo)
 
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<StructureSection load='6m0t' size='340' side='right'caption='[[6m0t]], [[Resolution|resolution]] 2.68&Aring;' scene=''>
<StructureSection load='6m0t' size='340' side='right'caption='[[6m0t]], [[Resolution|resolution]] 2.68&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6m0t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M0T FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6m0t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M0T FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EZ3:(3R)-3-[(R)-[(2R,6S)-6-methyloxan-2-yl]-oxidanyl-methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one'>EZ3</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.68&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4pg3|4pg3]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EZ3:(3R)-3-[(R)-[(2R,6S)-6-methyloxan-2-yl]-oxidanyl-methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one'>EZ3</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PF3D7_1350100 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysine--tRNA_ligase Lysine--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.6 6.1.1.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m0t OCA], [https://pdbe.org/6m0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m0t RCSB], [https://www.ebi.ac.uk/pdbsum/6m0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m0t ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m0t OCA], [https://pdbe.org/6m0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m0t RCSB], [https://www.ebi.ac.uk/pdbsum/6m0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m0t ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8IDJ8_PLAF7 Q8IDJ8_PLAF7]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lysine--tRNA ligase]]
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[[Category: Plasmodium falciparum 3D7]]
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[[Category: Plaf7]]
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[[Category: Babbar P]]
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[[Category: Babbar, P]]
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[[Category: Manickam Y]]
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[[Category: Manickam, Y]]
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[[Category: Sharma A]]
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[[Category: Sharma, A]]
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[[Category: Cladosporin analog]]
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[[Category: Ligase-ligase inhibitor complex]]
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[[Category: Stereochemistry]]
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Current revision

Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Cladosporin derivative (CL-2)

PDB ID 6m0t

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