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6y0l

From Proteopedia

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Current revision (13:16, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6y0l' size='340' side='right'caption='[[6y0l]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='6y0l' size='340' side='right'caption='[[6y0l]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6y0l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y0L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6y0l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y0L FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FCER2, CD23A, CLEC4J, FCE2, IGEBF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y0l OCA], [https://pdbe.org/6y0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y0l RCSB], [https://www.ebi.ac.uk/pdbsum/6y0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y0l ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y0l OCA], [https://pdbe.org/6y0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y0l RCSB], [https://www.ebi.ac.uk/pdbsum/6y0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y0l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/FCER2_HUMAN FCER2_HUMAN]] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
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[https://www.uniprot.org/uniprot/FCER2_HUMAN FCER2_HUMAN] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Davies, A M]]
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[[Category: Davies AM]]
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[[Category: Ilkow, V F]]
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[[Category: Ilkow VF]]
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[[Category: McDonnell, J M]]
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[[Category: McDonnell JM]]
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[[Category: Sutton, B J]]
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[[Category: Sutton BJ]]
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[[Category: Antibody receptor]]
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[[Category: C-type lectin]]
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[[Category: Calcium binding protein]]
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[[Category: Cd23]]
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[[Category: Ige]]
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[[Category: Immune system]]
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[[Category: Immunoglobulin e]]
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Current revision

Crystal structure of human CD23 lectin domain N225D, K229E, S252N, T251N, R253G, S254G mutant

PDB ID 6y0l

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