Dihydroorotate dehydrogenase 3D structures
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 14: | Line 14: | ||
**[[3tjx]], [[3tro]] – LmDHOD (mutant) <br /> | **[[3tjx]], [[3tro]] – LmDHOD (mutant) <br /> | ||
**[[4wzh]] – DHOD + FMN – ''Leishmania braziliensis''<br /> | **[[4wzh]] – DHOD + FMN – ''Leishmania braziliensis''<br /> | ||
| - | **[[4zq6]] – DHOD + FMN – ''Mycobacterium tuberculosis''<br /> | + | **[[4zq6]], [[8ofw]] – DHOD + FMN – ''Mycobacterium tuberculosis''<br /> |
**[[6b8s]] – DHODH + FMN – ''Helicobacter pylori''<br /> | **[[6b8s]] – DHODH + FMN – ''Helicobacter pylori''<br /> | ||
**[[6uy4]] – DHODH + FMN – blood fluke<br /> | **[[6uy4]] – DHODH + FMN – blood fluke<br /> | ||
| Line 22: | Line 22: | ||
**[[3kvj]], [[3kvk]], [[3kvl]], [[3kvm]] – hDHOD + FMN + inhibitor - human<br /> | **[[3kvj]], [[3kvk]], [[3kvl]], [[3kvm]] – hDHOD + FMN + inhibitor - human<br /> | ||
**[[2bxv]] – hDHOD + FMN + orotate<br /> | **[[2bxv]] – hDHOD + FMN + orotate<br /> | ||
| + | **[[7z6c]] – hDHODH + FMN + inhibitor<br /> | ||
**[[2e68]] – hDHOD + FMN + dihydroorotate<br /> | **[[2e68]] – hDHOD + FMN + dihydroorotate<br /> | ||
**[[2dor]] - LlDHOD A + FMN + orotate <br /> | **[[2dor]] - LlDHOD A + FMN + orotate <br /> | ||
| Line 40: | Line 41: | ||
* Dihydroorotate dehydrogenase (quinone) | * Dihydroorotate dehydrogenase (quinone) | ||
| - | **[[3kvj]], [[3kvk]], [[3kvl]], [[3kvm]], [[6gk0]] – hDHODH + FMN + inhibitor<br /> | + | **[[3kvj]], [[3kvk]], [[3kvl]], [[3kvm]], [[6gk0]], [[8k4f]], [[8rak]], [[9i2y]] – hDHODH + FMN + inhibitor<br /> |
**[[1d3h]] – hDHODH + FMN + orotate + cell growth retarding drug <br /> | **[[1d3h]] – hDHODH + FMN + orotate + cell growth retarding drug <br /> | ||
**[[4igh]] - hDHODH + FMN + quinoline derivative<br /> | **[[4igh]] - hDHODH + FMN + quinoline derivative<br /> | ||
**[[3f1q]], [[3fj6]], [[3fjl]], [[3g0u]], [[3g0x]] – hDHODH + FMN + orotate + leflunomide<br /> | **[[3f1q]], [[3fj6]], [[3fjl]], [[3g0u]], [[3g0x]] – hDHODH + FMN + orotate + leflunomide<br /> | ||
**[[6lzl]] – hDHODH + FMN + orotate + piperine<br /> | **[[6lzl]] – hDHODH + FMN + orotate + piperine<br /> | ||
| - | **[[3w7r]], [[3u2o]], [[3zws]], [[3zwt]], [[4jgd]], [[4js3]], [[4jts]], [[1d3g]], [[1uuo]], [[2b0m]], [[2fpt]], [[2fpv]], [[2fpy]], [[2fqi]], [[2wv8]], [[4jtt]], [[4jtu]], [[4ls0]], [[4ls1]], [[4ls2]], [[4oqv]], [[4rk8]], [[4rka]], [[4rli]], [[4rr4]], [[4ylw]], [[4zl1]], [[4zmg]], [[5h2z]], [[5hin]], [[5hqe]], [[5k9c]], [[5k9d]], [[5mut]], [[5mvc]], [[5mvd]], [[5h73]], [[5zf9]], [[6cjg]], [[6et4]], [[5zf4]], [[5zf7]], [[5zf8]], [[5zfa]], [[5zfb]], [[6cjf]], [[6fmd]], [[6qu7]], [[6idj]], [[6j3b]], [[6j3c]], [[6jmd]], [[6jme]], [[6lp6]], [[6lp7]], [[6lp8]], [[6m2b]], [[6oc0]], [[6oc1]], [[6syp]], [[6vnd]], [[7k2u]] – hDHODH + FMN + orotate + inhibitor<br /> | + | **[[3w7r]], [[3u2o]], [[3zws]], [[3zwt]], [[4jgd]], [[4js3]], [[4jts]], [[1d3g]], [[1uuo]], [[2b0m]], [[2fpt]], [[2fpv]], [[2fpy]], [[2fqi]], [[2wv8]], [[4jtt]], [[4jtu]], [[4ls0]], [[4ls1]], [[4ls2]], [[4oqv]], [[4rk8]], [[4rka]], [[4rli]], [[4rr4]], [[4ylw]], [[4zl1]], [[4zmg]], [[5h2z]], [[5hin]], [[5hqe]], [[5k9c]], [[5k9d]], [[5mut]], [[5mvc]], [[5mvd]], [[5h73]], [[5zf9]], [[6cjg]], [[6et4]], [[5zf4]], [[5zf7]], [[5zf8]], [[5zfa]], [[5zfb]], [[6cjf]], [[6fmd]], [[6qu7]], [[6idj]], [[6j3b]], [[6j3c]], [[6jmd]], [[6jme]], [[6lp6]], [[6lp7]], [[6lp8]], [[6m2b]], [[6oc0]], [[6oc1]], [[6syp]], [[6vnd]], [[7k2u]], [[8dhf]], [[8dhg]], [[8dhh]] – hDHODH + FMN + orotate + inhibitor<br /> |
**[[2prl]], [[2prm]], [[2prh]] – hDHODH (mutant) + FMN + orotate + inhibitor<br /> | **[[2prl]], [[2prm]], [[2prh]] – hDHODH (mutant) + FMN + orotate + inhibitor<br /> | ||
**[[6et4]] – hDHODH + FMN + inhibitor<br /> | **[[6et4]] – hDHODH + FMN + inhibitor<br /> | ||
| Line 52: | Line 53: | ||
**[[6aj5]] – cpDHODH + orotate + FMN - coccidian parasite<br /> | **[[6aj5]] – cpDHODH + orotate + FMN - coccidian parasite<br /> | ||
**[[6aje]] – cpDHODH + orotate + FMN + ferulenol<br /> | **[[6aje]] – cpDHODH + orotate + FMN + ferulenol<br /> | ||
| - | **[[1tv5]], [[3i65]], [[3i68]], [[3i6r]], [[3o8a]], [[3sfk]], [[4cq8]], [[4cq9]], [[4cqa]], [[4orm]], [[4rx0]], [[5boo]], [[5fi8]], [[6i55]], [[6gjg]], [[6i4b]], [[6vtn]], [[6vty]], [[7kyk]], [[7kyv]], [[7kyy]], [[7kz4]], [[7l01]], [[7l0k]] - PfDHODH + FMN + orotate + inhibitor | + | **[[7wyf]] – PfDHODH + FMN + inhibitor – ''Plasmodium falciparum''<br /> |
| + | **[[1tv5]], [[3i65]], [[3i68]], [[3i6r]], [[3o8a]], [[3sfk]], [[4cq8]], [[4cq9]], [[4cqa]], [[4orm]], [[4rx0]], [[5boo]], [[5fi8]], [[6i55]], [[6gjg]], [[6i4b]], [[6vtn]], [[6vty]], [[7kyk]], [[7kyv]], [[7kyy]], [[7kz4]], [[7kzy]], [[7l01]], [[7l0k]], [[7s87]] - PfDHODH + FMN + orotate + inhibitor <br /> | ||
**[[5del]], [[5tbo]], [[6e0b]] – PfDHODH (mutant) + FMN + orotate + inhibitor <br /> | **[[5del]], [[5tbo]], [[6e0b]] – PfDHODH (mutant) + FMN + orotate + inhibitor <br /> | ||
| - | **[[1f76]] – | + | **[[1f76]] – EcDHODH + FMN + orotate – ''Escherichia coli''<br /> |
| + | **[[7t6h]] – EcDHODH (mutant) + FMN + orotate <br /> | ||
| + | **[[7t5k]], [[7t5y]], [[7t6c]] – EcDHODH + FMN + orotate + inhibitor<br /> | ||
| + | **[[7ut5]] – DHODH + FMN + orotate + inhibitor – ''Acinetobacter baumanii''<br /> | ||
* Dihydroorotate dehydrogenase (fumarate) | * Dihydroorotate dehydrogenase (fumarate) | ||
| - | **[[ | + | **[[3w1q]], [[3w1r]], [[3w1t]], [[3w1u]], [[3w1x]], [[3w22]], [[3w23]], [[3w2j]], [[3w2k]], [[3w2l]], [[3w2m]], [[3w2n]], [[3w2u]], [[3w3o]], [[3w6y]], [[3w70]], [[3w71]], [[3w70]], [[3w71]], [[3w72]], [[3w73]], [[3w74]], [[3w75]], [[3w76]], [[3w7c]], [[3w7d]], [[3w7e]], [[3w7g]], [[3w7h]], [[3w7i]], [[3w7j]], [[3w7k]], [[3w7l]], [[3w7m]], [[3w7n]], [[3w7o]], [[3w7p]], [[3w7q]], [[3w83]], [[3w84]], [[3w85]], [[3w86]], [[3w87]], [[3w88]], [[4jd4]], [[4jdb]], [[5e93]], [[5ea9]] – TcDHODF + FMN + inhibitor<br /> |
**[[3w1p]] - TcDHODF + FMN + pyrimidine derivative<br /> | **[[3w1p]] - TcDHODF + FMN + pyrimidine derivative<br /> | ||
**[[3w1a]], [[3w1l]], [[3w1m]], [[3w1n]] - TcDHODF + FMN + orotate derivative<br /> | **[[3w1a]], [[3w1l]], [[3w1m]], [[3w1n]] - TcDHODF + FMN + orotate derivative<br /> | ||
| Line 65: | Line 70: | ||
**[[6dgs]], [[6dwg]] - LmDHODF (mutant) + FMN <br /> | **[[6dgs]], [[6dwg]] - LmDHODF (mutant) + FMN <br /> | ||
**[[6ebs]] - LmDHODF (mutant) + FMN + orotate<br /> | **[[6ebs]] - LmDHODF (mutant) + FMN + orotate<br /> | ||
| + | **[[7mx6]], [[7myd]] – LmDHODH + FMN + orotate + inhibitor <br /> | ||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
3D Structures of dihydroorotate dehydrogenase
Updated on 06-April-2025
