7f84
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of CRISPR-associated Cas2c of Leptospira interrogans== | |
| - | + | <StructureSection load='7f84' size='340' side='right'caption='[[7f84]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7f84]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leptospira_interrogans_serovar_Copenhageni_str._Fiocruz_L1-130 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7F84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7F84 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7f84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7f84 OCA], [https://pdbe.org/7f84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7f84 RCSB], [https://www.ebi.ac.uk/pdbsum/7f84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7f84 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q72NB8_LEPIC Q72NB8_LEPIC] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.[HAMAP-Rule:MF_01471] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]] | ||
| + | [[Category: Anand V]] | ||
| + | [[Category: Gogoi P]] | ||
| + | [[Category: Kanaujia SP]] | ||
| + | [[Category: Kumar M]] | ||
| + | [[Category: Prabhakaran HS]] | ||
Current revision
Crystal structure of CRISPR-associated Cas2c of Leptospira interrogans
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