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1cf1

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Current revision (23:26, 27 December 2023) (edit) (undo)
 
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<StructureSection load='1cf1' size='340' side='right'caption='[[1cf1]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1cf1' size='340' side='right'caption='[[1cf1]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1cf1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CF1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1cf1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CF1 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cf1 OCA], [https://pdbe.org/1cf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cf1 RCSB], [https://www.ebi.ac.uk/pdbsum/1cf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cf1 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cf1 OCA], [https://pdbe.org/1cf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cf1 RCSB], [https://www.ebi.ac.uk/pdbsum/1cf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cf1 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[https://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN]] Note=S-antigen induces autoimmune uveitis.
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[https://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN] Note=S-antigen induces autoimmune uveitis.
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN]] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade.
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[https://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bovin]]
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[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Gurevich, V V]]
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[[Category: Gurevich VV]]
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[[Category: Hirsch, J A]]
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[[Category: Hirsch JA]]
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[[Category: Schubert, C]]
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[[Category: Schubert C]]
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[[Category: Sigler, P B]]
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[[Category: Sigler PB]]
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[[Category: Binding to acticated and phosphorylated rhodopsin]]
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[[Category: Desensitisation of the visual transduction cascade]]
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[[Category: Structural protein]]
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[[Category: Visual arrestin]]
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Current revision

ARRESTIN FROM BOVINE ROD OUTER SEGMENTS

PDB ID 1cf1

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OCA

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