Esterification
From Proteopedia
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In the <jmol><jmolLink><script>anim mode once; frame range 11 19; delay 0.5; frame play</script><text>second step</text></jmolLink></jmol> the alcohol attacks the protonated carbonyl group to create a tetrahedral intermediate structure. | In the <jmol><jmolLink><script>anim mode once; frame range 11 19; delay 0.5; frame play</script><text>second step</text></jmolLink></jmol> the alcohol attacks the protonated carbonyl group to create a tetrahedral intermediate structure. | ||
In the <jmol><jmolLink><script>anim mode once; frame range 20 41; delay 0.5; frame play</script><text>third step</text></jmolLink></jmol> a proton is lost at one oxygen atom and bonds to another oxygen atom. | In the <jmol><jmolLink><script>anim mode once; frame range 20 41; delay 0.5; frame play</script><text>third step</text></jmolLink></jmol> a proton is lost at one oxygen atom and bonds to another oxygen atom. | ||
| - | In the <jmol><jmolLink><script>anim mode once; frame range 41 50; delay 0.5; frame play</script><text>fourth step</text></jmolLink></jmol> water molecule leaves the structure. | + | In the <jmol><jmolLink><script>anim mode once; frame range 41 50; delay 0.5; frame play</script><text>fourth step</text></jmolLink></jmol> a water molecule leaves the structure. |
| - | In the <jmol><jmolLink><script>anim mode once; frame range 51 59; delay 0.5; frame play</script><text>fifth step</text></jmolLink></jmol> . | + | In the <jmol><jmolLink><script>anim mode once; frame range 51 59; delay 0.5; frame play</script><text>fifth step</text></jmolLink></jmol> a proton (H+) leaves the carbonyl group, transfers to a base and '''ester''' is formed. |
[[Image:Esterification Mechanism.png|550px]] <br> | [[Image:Esterification Mechanism.png|550px]] <br> | ||
Current revision
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See also
SN1 reaction: Substitution of Cl− and tert-Butanol
SN2 reaction: substitution of Cl− and methanol
