1e8s

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<StructureSection load='1e8s' size='340' side='right'caption='[[1e8s]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
<StructureSection load='1e8s' size='340' side='right'caption='[[1e8s]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1e8s]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E8S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E8S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1e8s]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E8S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E8S FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EU3:EUROPIUM+(III)+ION'>EU3</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1e8o|1e8o]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EU3:EUROPIUM+(III)+ION'>EU3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e8s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e8s OCA], [https://pdbe.org/1e8s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e8s RCSB], [https://www.ebi.ac.uk/pdbsum/1e8s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e8s ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e8s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e8s OCA], [https://pdbe.org/1e8s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e8s RCSB], [https://www.ebi.ac.uk/pdbsum/1e8s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e8s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/SRP09_HUMAN SRP09_HUMAN]] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. [[https://www.uniprot.org/uniprot/SRP14_HUMAN SRP14_HUMAN]] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
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[https://www.uniprot.org/uniprot/SRP09_HUMAN SRP09_HUMAN] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Signal recognition particle protein|Signal recognition particle protein]]
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*[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cusack, S]]
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[[Category: Cusack S]]
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[[Category: Strub, K]]
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[[Category: Strub K]]
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[[Category: Weichenrieder, O]]
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[[Category: Weichenrieder O]]
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[[Category: Wild, K]]
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[[Category: Wild K]]
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[[Category: Alu retroposition]]
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[[Category: Alu ribonucleoprotein particle]]
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[[Category: Alu rnp assembly and dimerisation]]
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[[Category: Translational control]]
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Current revision

Alu domain of the mammalian SRP (potential Alu retroposition intermediate)

PDB ID 1e8s

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