1f2s

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Current revision (06:02, 9 August 2023) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1f2s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Momordica_charantia Momordica charantia]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1mcu 1mcu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F2S FirstGlance]. <br>
<table><tr><td colspan='2'>[[1f2s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Momordica_charantia Momordica charantia]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1mcu 1mcu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F2S FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1mct|1mct]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f2s OCA], [https://pdbe.org/1f2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f2s RCSB], [https://www.ebi.ac.uk/pdbsum/1f2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f2s ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f2s OCA], [https://pdbe.org/1f2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f2s RCSB], [https://www.ebi.ac.uk/pdbsum/1f2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f2s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ITR2_MOMCH ITR2_MOMCH]] Inhibits trypsin.
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[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Momordica charantia]]
[[Category: Momordica charantia]]
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[[Category: Trypsin]]
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[[Category: Huang Q]]
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[[Category: Huang, Q]]
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[[Category: Jia Y]]
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[[Category: Jia, Y]]
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[[Category: Qian M]]
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[[Category: Qian, M]]
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[[Category: Tang Y]]
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[[Category: Tang, Y]]
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[[Category: Zhu Y]]
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[[Category: Zhu, Y]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Proteinase-inhibitor complex]]
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Current revision

CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN BOVINE BETA-TRYPSIN AND MCTI-A, A TRYPSIN INHIBITOR OF SQUASH FAMILY AT 1.8 A RESOLUTION

PDB ID 1f2s

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OCA

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