7cme

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (16:10, 29 November 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 7cme is ON HOLD until Oct 27 2022
+
==Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor)==
 +
<StructureSection load='7cme' size='340' side='right'caption='[[7cme]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[7cme]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CME OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CME FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=G60:2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine'>G60</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cme FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cme OCA], [https://pdbe.org/7cme PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cme RCSB], [https://www.ebi.ac.uk/pdbsum/7cme PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cme ProSAT]</span></td></tr>
 +
</table>
 +
== Disease ==
 +
[https://www.uniprot.org/uniprot/CADH3_HUMAN CADH3_HUMAN] Hypotrichosis with juvenile macular degeneration;EEM syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CADH3_HUMAN CADH3_HUMAN] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
-
Authors: Senoo, A., Ito, S., Ueno, G., Nagatoishi, S., Tsumoto, K.
+
==See Also==
-
 
+
*[[Cadherin 3D structures|Cadherin 3D structures]]
-
Description: Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor)
+
__TOC__
-
[[Category: Unreleased Structures]]
+
</StructureSection>
-
[[Category: Ito, S]]
+
[[Category: Homo sapiens]]
-
[[Category: Ueno, G]]
+
[[Category: Large Structures]]
-
[[Category: Nagatoishi, S]]
+
[[Category: Ito S]]
-
[[Category: Tsumoto, K]]
+
[[Category: Nagatoishi S]]
-
[[Category: Senoo, A]]
+
[[Category: Senoo A]]
 +
[[Category: Tsumoto K]]
 +
[[Category: Ueno G]]

Current revision

Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor)

PDB ID 7cme

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7cme"
Personal tools