7p71
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7p71 is ON HOLD until Paper Publication Authors: Gogl, G., Cousido-Siah, A., Trave, G. Description: The PDZ domain of MAGI1_2 complexed with the PD...) |
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- | '''Unreleased structure''' | ||
- | The | + | ==The PDZ domain of MAGI1_2 complexed with the PDZ-binding motif of HPV35-E6== |
- | + | <StructureSection load='7p71' size='340' side='right'caption='[[7p71]], [[Resolution|resolution]] 2.60Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[7p71]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_papillomavirus_35 Human papillomavirus 35]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P71 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p71 OCA], [https://pdbe.org/7p71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p71 RCSB], [https://www.ebi.ac.uk/pdbsum/7p71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p71 ProSAT]</span></td></tr> |
- | [[Category: | + | </table> |
- | [[Category: Cousido-Siah | + | == Function == |
+ | [https://www.uniprot.org/uniprot/MAGI1_HUMAN MAGI1_HUMAN] May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).[https://www.uniprot.org/uniprot/ANXA2_HUMAN ANXA2_HUMAN] Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Human papillomavirus 35]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Cousido-Siah A]] | ||
+ | [[Category: Gogl G]] | ||
+ | [[Category: Trave G]] |
Current revision
The PDZ domain of MAGI1_2 complexed with the PDZ-binding motif of HPV35-E6
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