1gu0

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Current revision (12:06, 13 December 2023) (edit) (undo)
 
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<StructureSection load='1gu0' size='340' side='right'caption='[[1gu0]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1gu0' size='340' side='right'caption='[[1gu0]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1gu0]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/"actinomyces_coelicolor"_(muller_1908)_lieske_1921 "actinomyces coelicolor" (muller 1908) lieske 1921]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GU0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1gu0]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GU0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1d0i|1d0i]], [[1gqn|1gqn]], [[1gqo|1gqo]], [[1gtz|1gtz]], [[1gu1|1gu1]], [[2dhq|2dhq]], [[1qfe|1qfe]], [[1guy|1guy]], [[1gvz|1gvz]], [[1gv1|1gv1]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gu0 OCA], [https://pdbe.org/1gu0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gu0 RCSB], [https://www.ebi.ac.uk/pdbsum/1gu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gu0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gu0 OCA], [https://pdbe.org/1gu0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gu0 RCSB], [https://www.ebi.ac.uk/pdbsum/1gu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gu0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/AROQ_STRCO AROQ_STRCO]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
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[https://www.uniprot.org/uniprot/AROQ_STRCO AROQ_STRCO] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-dehydroquinate dehydratase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Coggins, J R]]
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[[Category: Streptomyces coelicolor]]
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[[Category: Hunter, I S]]
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[[Category: Coggins JR]]
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[[Category: Krell, T]]
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[[Category: Hunter IS]]
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[[Category: Lapthorn, A J]]
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[[Category: Krell T]]
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[[Category: Robinson, D]]
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[[Category: Lapthorn AJ]]
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[[Category: Roszak, A W]]
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[[Category: Robinson D]]
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[[Category: Dodecameric quaternary structure]]
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[[Category: Roszak AW]]
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[[Category: Lyase]]
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[[Category: Shikimate pathway]]
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[[Category: Tetrahedral symmetry]]
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[[Category: Type ii dehydroquinase]]
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Current revision

CRYSTAL STRUCTURE OF TYPE II DEHYDROQUINASE FROM STREPTOMYCES COELICOLOR

PDB ID 1gu0

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