7rnu

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(New page: '''Unreleased structure''' The entry 7rnu is ON HOLD Authors: Dai, S., Horton, J.R., Cheng, X. Description: nSH2 domain of p85-beta subunit of phosphatidylinositol 3-kinase in complex ...)
Current revision (16:34, 18 October 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7rnu is ON HOLD
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==nSH2 domain of p85-beta subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53==
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<StructureSection load='7rnu' size='340' side='right'caption='[[7rnu]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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Authors: Dai, S., Horton, J.R., Cheng, X.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7rnu]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RNU FirstGlance]. <br>
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Description: nSH2 domain of p85-beta subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
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[[Category: Cheng, X]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rnu OCA], [https://pdbe.org/7rnu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rnu RCSB], [https://www.ebi.ac.uk/pdbsum/7rnu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rnu ProSAT]</span></td></tr>
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[[Category: Dai, S]]
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</table>
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[[Category: Horton, J.R]]
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== Function ==
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[https://www.uniprot.org/uniprot/P85B_HUMAN P85B_HUMAN] Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Cheng X]]
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[[Category: Dai S]]
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[[Category: Horton JR]]

Current revision

nSH2 domain of p85-beta subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53

PDB ID 7rnu

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