1j2g

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Current revision (23:41, 27 December 2023) (edit) (undo)
 
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<StructureSection load='1j2g' size='340' side='right'caption='[[1j2g]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1j2g' size='340' side='right'caption='[[1j2g]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1j2g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacsb Bacsb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J2G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1j2g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._TB-90 Bacillus sp. TB-90]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J2G FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZA:8-AZAXANTHINE'>AZA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1uox|1uox]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZA:8-AZAXANTHINE'>AZA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Factor_independent_urate_hydroxylase Factor independent urate hydroxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.3.3 1.7.3.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j2g OCA], [https://pdbe.org/1j2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j2g RCSB], [https://www.ebi.ac.uk/pdbsum/1j2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j2g ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j2g OCA], [https://pdbe.org/1j2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j2g RCSB], [https://www.ebi.ac.uk/pdbsum/1j2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j2g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PUCL_BACSB PUCL_BACSB]] Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin (By similarity).
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[https://www.uniprot.org/uniprot/PUCL_BACSB PUCL_BACSB] Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Urate Oxidase|Urate Oxidase]]
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*[[Urate oxidase 3D structures|Urate oxidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacsb]]
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[[Category: Bacillus sp. TB-90]]
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[[Category: Factor independent urate hydroxylase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hibi, T]]
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[[Category: Hibi T]]
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[[Category: Nago, T]]
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[[Category: Nago T]]
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[[Category: Nishiya, Y]]
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[[Category: Nishiya Y]]
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[[Category: Oda, J]]
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[[Category: Oda J]]
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[[Category: Oxidoreductase]]
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[[Category: Purine]]
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[[Category: T-fold barrel]]
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Current revision

Crystal structure of Urate oxidase from Bacillus SP. TB-90 co-crystallized with 8-Azaxanthine

PDB ID 1j2g

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