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| - | | + | #REDIRECT [[8p7h]] This PDB entry is obsolete and replaced by 8p7h |
| - | ==Phosphotriesterase PTE_A53_2==
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| - | <StructureSection load='6fef' size='340' side='right'caption='[[6fef]], [[Resolution|resolution]] 1.77Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[6fef]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FEF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FEF FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6fee|6fee]]</div></td></tr>
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| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">opd ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aryldialkylphosphatase Aryldialkylphosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.1 3.1.8.1] </span></td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fef OCA], [https://pdbe.org/6fef PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fef RCSB], [https://www.ebi.ac.uk/pdbsum/6fef PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fef ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[https://www.uniprot.org/uniprot/OPD_BREDI OPD_BREDI]] Has an unusual substrate specificity for synthetic organophosphate triesters and phosphorofluoridates. All of the phosphate triesters found to be substrates are synthetic compounds. The identity of any naturally occurring substrate for the enzyme is unknown. Has no detectable activity with phosphate monoesters or diesters and no activity as an esterase or protease. It catalyzes the hydrolysis of the insecticide paraoxon at a rate approaching the diffusion limit and thus appears to be optimally evolved for utilizing this synthetic substrate.
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| - | ==See Also==
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| - | *[[Phosphotriesterase 3D structures|Phosphotriesterase 3D structures]]
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Bacillus coli migula 1895]]
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| - | [[Category: Aryldialkylphosphatase]]
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| - | [[Category: Large Structures]]
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| - | [[Category: Aggarwal, N]]
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| - | [[Category: Albeck, S]]
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| - | [[Category: Ashani, Y]]
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| - | [[Category: Dym, O]]
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| - | [[Category: Goldsmith, M]]
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| - | [[Category: Greisen, P]]
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| - | [[Category: Leader, H]]
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| - | [[Category: Rogotner, S Hamer]]
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| - | [[Category: Silman, I]]
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| - | [[Category: Sussman, L J]]
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| - | [[Category: Tawfik, D]]
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| - | [[Category: Unger, T]]
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| - | [[Category: Hydrolase]]
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| - | [[Category: Metalloenzyme]]
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| - | [[Category: Tim barrel]]
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