Gp120 3D structures

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**[[3dnl]], [[3dnn]], [[3dno]], [[3tgq]], [[3tgr]], [[3tgt]], [[3tih]], [[5f4u]], [[6utb]], [[6utd]] - Gp120 core<br />
**[[3dnl]], [[3dnn]], [[3dno]], [[3tgq]], [[3tgr]], [[3tgt]], [[3tih]], [[5f4u]], [[6utb]], [[6utd]] - Gp120 core<br />
-
**[[5fa2]] - Gp120 core (mutant)<br />
+
**[[5fa2]], [[8gd5]], [[8gdk]], [[8gjt]] - Gp120 core (mutant)<br />
**[[1meq]] – GP120 C5 domain – NMR<br />
**[[1meq]] – GP120 C5 domain – NMR<br />
**[[1niz]], [[1nj0]], [[2esx]], [[2esz]], [[1u6u]], [[1u6v]] - GP120 V3 loop – NMR<br />
**[[1niz]], [[1nj0]], [[2esx]], [[2esz]], [[1u6u]], [[1u6v]] - GP120 V3 loop – NMR<br />
**[[4jpj]], [[5idl]] - Gp120 outer domain<br />
**[[4jpj]], [[5idl]] - Gp120 outer domain<br />
 +
**[[9bxb]], [[9bxd]], [[9bxw]], [[9bxy]] - Gp120 Clade A/E
 +
**[[8gdj]] - Gp120 Clade A/E (mutant)
-
*Gp120 binary complex
+
*Gp120+antibody binary complex
-
**[[4jb9]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lsu]], [[5te6]], [[5fcu]], [[5f9w]], [[5f9o]], [[5f96]], [[5cd5]], [[4xvt]] - Gp120 Clade A/E + antibody <br />
+
**[[4jb9]], [[4jpj]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lsu]], [[4olu]], [[4olv]], [[4olx]], [[4olz]], [[4om0]], [[4om1]], [[4rx4]], [[4xmp]], [[4ydi]], [[4ydj]], [[4ydk]], [[5i9q]], [[5te6]], [[5fcu]], [[5f9w]], [[5f9o]], [[5f96]], [[5cd5]], [[4xvt]], [[6oej]], [[6p8m]], [[6xcj]], [[7jks]], [[7jkt]], [[7klc]], [[7kmd]], [[7n8q]] - Gp120 Clade A/E + antibody <br />
-
**[[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]] - Gp120 Clade A/E (mutant) + antibody <br />
+
**[[4xnz]], [[6n1w]], [[7mep]], [[8u1d]] - Gp120 Clade A/E + antibody – Cryo EM<br />
-
**[[4i3r]], [[4i3s]], [[5kzc]], [[5if0]], [[5ies]], [[4jpv]] - Gp120 outer domain + antibody<br />
+
**[[3u7y]], [[4jpw]], [[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]], [[6ofi]], [[9mj3]] - Gp120 Clade A/E (mutant) + antibody <br />
 +
**[[4olw]], [[4oly]], [[7sx6]], [[7sx7]] - Gp120 core + antibody<br />
 +
**[[3tyg]], [[4i3r]], [[4i3s]], [[5kzc]], [[5if0]], [[5ies]], [[4jpv]], [[9mic]] - Gp120 outer domain + antibody<br />
**[[5t33]] - Gp120 RHPA + antibody <br />
**[[5t33]] - Gp120 RHPA + antibody <br />
**[[3u2s]] - Gp120 V1V2 region + antibody PG9<br />
**[[3u2s]] - Gp120 V1V2 region + antibody PG9<br />
-
**[[3se8]], [[3se9]], [[3hi1]], [[3rjq]], [[4jkp]], [[4jm2]], [[4lss]], [[4lsv]], [[4ywg]], [[4xvs]], [[3ngb]], [[4ye4]], [[4rwy]], [[4jan]], [[4lst]], [[5te7]], [[5f6j]], [[5te4]], [[6bf4]], [[5wb9]], [[5w6d]], [[5ukr]], [[5uem]], [[5igx]], [[4dvr]] - Gp120 core + antibody<br />
+
**[[3hi1]], [[3ngb]], [[3rjq]], [[3se8]], [[3se9]], [[4dvr]], [[4jan]], [[4jkp]], [[4jm2]], [[4lss]], [[4lst]], [[4lsv]], [[4ye4]], [[4xvs]], [[4ywg]], [[4rwy]], [[5te7]], [[5f6j]], [[5te4]], [[5wb9]], [[5w6d]], [[5ukr]], [[5uem]], [[5igx]], [[6bf4]], [[9cf6]], [[9cfa]], [[9oao]], [[9oap]], [[9oaq]], [[9oar]], [[9oas]] - Gp120 core + antibody<br />
-
**[[3idx]], [[3idy]], [[2ny7]], [[4jdt]], [[5fyl]], [[5fec]], [[6bck]], [[6p8m]], [[6oz2]], [[6oz3]] - Gp120 core (mutant) + antibody <br />
+
**[[2ny7]], [[3idx]], [[3idy]], [[4jdt]], [[5fec]], [[5fyl]], [[6bck]], [[6oz2]], [[6oz3]] - Gp120 core (mutant) + antibody <br />
-
**[[6p8m]], [[6xcj]] - Gp120 44-494 + antibody <br />
+
**[[3mls]], [[3mlw]], [[4jo3]], [[6db5]], [[6db7]] - Gp120 V3 + antibody <br />
-
**[[6v0r]], [[6vfl]], [[6vrw]], [[7l7t]], [[7l7u]] - Gp120 33-513 + Gp41 – Cryo EM <br />
+
**[[1qnz]] - Gp120 V3 + antibody - NMR<br />
 +
**[[6cez]], [[6vbo]], [[6vbp]], [[6vbq]] - Gp120 V2 + antibody <br />
 +
**[[7r73]], [[7r74]], [[7ri1]], [[7ri2]] - Gp120 core + VHH <br />
 +
 
 +
*Gp120 other binary complex
 +
 
 +
**[[6v0r]], [[6vfl]], [[6vrw]], [[7l7t]], [[7l7u]], [[6vfl]], [[7sc5]], [[7ska]], [[8f7t]], [[8fad]], [[8fae]] - Gp120 Clade A/E + Gp41 core – Cryo EM<br />
 +
**[[7l6o]] - Gp120 Clade A/E (mutant) + Gp41 core <br />
 +
**[[8tgw]] - Gp120 Clade A/E (mutant) + Gp41 core (mutant) – Cryo EM<br />
 +
**[[6vl5]] - Gp120 Clade A/E + Gp41 core – synthetic - Cryo EM<br />
 +
**[[4i54]], [[7rsx]], [[7rsy]], [[7rsz]], [[7tjo]], [[7tjp]], [[8dcq]], [[8fly]], [[8flz]], [[8fm0]], [[8fm2]], [[8fm3]], [[8fm4]], [[8fm5]], [[8fm7]], [[8fm8]] - Gp120 Clade A/E + inhibitor <br />
 +
**[[4i53]], [[7rdw]], [[8f9z]] - Gp120 core + inhibitor <br />
 +
**[[6usw]], [[8fa0]] - Gp120 core (mutant) + inhibitor <br />
**[[6l1y]] - Gp120 core + CD4 <br />
**[[6l1y]] - Gp120 core + CD4 <br />
**[[4rz8]], [[5f4l]], [[5f4p]], [[5f4r]] - Gp120 core + CD4 mimic <br />
**[[4rz8]], [[5f4l]], [[5f4p]], [[5f4r]] - Gp120 core + CD4 mimic <br />
**[[4dku]], [[4dkv]] - Gp120 core (mutant) + CD4 mimetic<br />
**[[4dku]], [[4dkv]] - Gp120 core (mutant) + CD4 mimetic<br />
**[[4jzw]], [[4jzz]], [[4k0a]], [[4ka2]] - Gp120 core + CD4 mimetic miniprotein<br />
**[[4jzw]], [[4jzz]], [[4k0a]], [[4ka2]] - Gp120 core + CD4 mimetic miniprotein<br />
-
**[[4jpj]], [[4rx4]] - Gp120 Clade A + antibody <br />
+
**[[6one]], [[6onf]], [[6onh]], [[6onv]], [[6p9n]] - Gp120 Clade A/E (mutant) + CD4 mimetic<br />
-
**[[7klc]] - Gp120 Clade A 43-126,194-489 + antibody <br />
+
-
**[[7jks]], [[7jkt]] - Gp120 43-510 + antibody <br />
+
-
**[[6one]], [[6onf]], [[6onh]], [[6onv]], [[6ooo]], [[6p9n]] - Gp120 Clade A/E (mutant) + CD4 mimetic<br />
+
**[[3tgs]], [[4dko]], [[4dkp]], [[4dkq]], [[4dkr]], [[6ooo]] - Gp120 core + piperidine derivative<br />
**[[3tgs]], [[4dko]], [[4dkp]], [[4dkq]], [[4dkr]], [[6ooo]] - Gp120 core + piperidine derivative<br />
**[[5u6e]] - Gp120 core + pyrrole derivative<br />
**[[5u6e]] - Gp120 core + pyrrole derivative<br />
-
**[[4dvx]], [[4dvw]], [[4dvv]], [[4dvt]], [[4dvs]], [[6uw]] - Gp120 core (mutant) + piperazine derivative<br />
+
**[[4dvx]], [[4dvw]], [[4dvv]], [[4dvt]], [[4dvs]], [[6usw]] - Gp120 core (mutant) + piperazine derivative<br />
**[[6ut1]] - Gp120 core (mutant) + inhibitor<br />
**[[6ut1]] - Gp120 core (mutant) + inhibitor<br />
 +
**[[8gcz]], [[8gd1]], [[8gd3]] - Gp120 Clade A/E (mutant) + piperidine derivative
-
*Gp120 ternary complex
+
*Gp120 higher complex
**[[5kjr]], [[6mfp]] - Gp120 Clade A/E + M48U1 peptide + antibody<br />
**[[5kjr]], [[6mfp]] - Gp120 Clade A/E + M48U1 peptide + antibody<br />
**[[4rfo]], [[4rfn]], [[6mg7]] - Gp120 Clade A/E 4-492 (mutant) + M48U1 peptide + antibody<br />
**[[4rfo]], [[4rfn]], [[6mg7]] - Gp120 Clade A/E 4-492 (mutant) + M48U1 peptide + antibody<br />
-
**[[4h8w]] - Gp120 Clade A/E + CD4 + antibody<br />
+
**[[2qad]], [[3lqa]], [[4h8w]] - Gp120 Clade A/E + CD4 + antibody<br />
 +
**[[4tvp]], [[6utk]], [[6vkn]], [[6v6w]], [[7kmd]], [[7ucf]], [[8d0y]], [[8d50]] - Gp120 Clade A/E + Gp41 core + antibody <br />
 +
**[[3j5m]], [[6mpg]], [[6mph]], [[6n1v]], [[6n1w]], [[6nf2]], [[6nfc]], [[6x96]], [[6x97]], [[7kde]], [[7lg6]], [[7lu9]], [[7lxm]], [[7lxn]], [[7ly9]], [[7mdt]], [[7mdu]], [[7mxe]], [[7n28]], [[7pc2]], [[7rsn]], [[7rso]], [[7sd3]], [[7sq1]], [[7t73]], [[7t74]], [[7t75]], [[7t76]], [[7t77]], [[7t9a]], [[7t9b]], [[7tco]], [[7tfn]], [[7tfo]], [[7ugn]], [[7ugp]], [[7ugq]], [[7ur6]], [[7z3a]], [[7zlk]], [[8d4r]], [[8d53]], [[8dok]], [[8dow]], [[8dp1]], [[8euu]], [[8euv]], [[8euw]], [[8f92]], [[8f9g]], [[8f9m]], [[8fis]], [[8fk5]], [[8fl1]], [[8flw]], [[8g4m]], [[8g85]], [[8g9w]], [[8g9x]], [[8g9y]], [[8gas]], [[8jtd]], [8jtm]], [[8s2e]], [[8sal]], [[8san]], [[8saq]], [[8sar]], [[8sas]], [[8sat]], [[8sau]], [[8sav]], [[8saw]], [[8sax]], [[8say]], [[8sb0]], [[8sb1]], [[8sb2]], [[8sb3]], [[8sb4]], [[8sb5]], [[8sw3]], [[8sw4]], [[8sw7]], [[8sww]], [[8swx]], [[8t2e]], [[8t2f]][[8t49]], [[8t4a]], [[8t4b]], [[8t4d]], [[8t4k]], [[8t4l]], [[8tgo]], [[8tng]], [[8tnh]], [[8tni]]. [[8tnu]], [[8to7]], [[8to9]], [[8top]], [[8tox]], [[8tq1]], [[8ult]], [[8ulu]], [[8vfv]], [[8vgv]], [[8vgw]], [[8vh1]], [[8vh3]], [[9atz]], [[9aug]], [[9auh]], [[9aui]], [[9axd]], [[9axi]], [[9axk]], [[9ay6]], [[9ays]], [[9ayv]], [[9ber]], [[9bew]], [[9bf6]], [[9bnk]], [[9bnl]], [[9bnm]], [[9bnp]], [[9bth]], [[9bti]], [[9btj]], [[9btl]], [[9btv]], [[9d1w]], [[9d3d]], [[9d7g]], [[9d7h]], [[9d7i]], [[9d7o]], [[9d7p]], [[9d98]], [[9dmb]], [[9ehl]], [[9ehm]], [[9evz]], [[9nhh]], [[9nhi]], [[9nhj]], [[9nhk]], [[9nhl]], [[9nhm]], [[9nhn]], [[9nho]], [[9ni9]] - Gp120 Clade A/E + Gp41 core + antibody – Cryo EM<br />
 +
**[[6ot1]], [[8czz]], [[8dto]], [[8g6u]], [[8swv]] - Gp120 Clade A/E (mutant) + Gp41 core + antibody – Cryo EM<br />
 +
**[[6x98]], [[7uoj]], [[8fr6]], [[8g4t]], [[8gje]], [[8tkc]], [[8tl2]], [[8tl3]], [[8tl4]], [[8tl5]], [[8tr3]] - Gp120 Clade A/E (mutant) + Gp41 core (mutant) + antibody – Cryo EM<br />
 +
**[[9d90]] - Gp120 Clade A/E (mutant) + Gp41 core (mutant) + antibody + CD4 – Cryo EM<br />
 +
**[[7lpn]] - Gp120 Clade A/E + Gp41 core + VHH – Cryo EM<br />
 +
**[[8vh2]], [[9mi0]], [[9mia]], [[9mib]], [[9mif]], [[9mih]], [[9mii]] - Gp120 Clade A/E + Gp160 + antibody – Cryo EM<br />
**[[3jwd]], [[3jwo]], [[2i5y]], [[2i60]] - Gp120 core + hCD4 N terminal + antibody <br />
**[[3jwd]], [[3jwo]], [[2i5y]], [[2i60]] - Gp120 core + hCD4 N terminal + antibody <br />
**[[2nxy]], [[2nxz]], [[2ny0]], [[2ny1]], [[2ny2]], [[2ny3]], [[2ny4]], [[2ny5]], [[2ny6]], [[1gc1]], [[1g9m]], [[1g9n]], [[1rzj]], [[1rzk]], [[1yyl]], [[1yym]], [[2b4c]] - Gp120 core (mutant) + hCD4 N terminal + antibody <br />
**[[2nxy]], [[2nxz]], [[2ny0]], [[2ny1]], [[2ny2]], [[2ny3]], [[2ny4]], [[2ny5]], [[2ny6]], [[1gc1]], [[1g9m]], [[1g9n]], [[1rzj]], [[1rzk]], [[1yyl]], [[1yym]], [[2b4c]] - Gp120 core (mutant) + hCD4 N terminal + antibody <br />
**[[5a8h]], [[5a7x]], [[4rqs]], [[4r4h]], [[4r2g]], [[4p9h]] - Gp120 core + hCD4 D1-D2 domain + antibody<br />
**[[5a8h]], [[5a7x]], [[4rqs]], [[4r4h]], [[4r2g]], [[4p9h]] - Gp120 core + hCD4 D1-D2 domain + antibody<br />
**[[4laj]] - Gp120 core + CD4 mimetic miniprotein + antibody<br />
**[[4laj]] - Gp120 core + CD4 mimetic miniprotein + antibody<br />
-
**[[5w4l]], [[6w4m]], [[6w4m]] - Gp120 core (mutant) + CD4 mimetic peptide + antibody<br />
+
**[[5w4l]], [[6w4m]] - Gp120 core (mutant) + CD4 mimetic peptide + antibody<br />
**[[4r4f]], [[4r4n]] - Gp120 core + M48U1 peptide + antibody<br />
**[[4r4f]], [[4r4n]] - Gp120 core + M48U1 peptide + antibody<br />
-
**[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k]], [[6mft]], [[6mdt]], [[6mco]], [[6d2p]], [[6ck9]], [[6ch9]], [[6ch8]], [[6ch7]] - Gp120 core + Gp41 + antibody<br />
+
**[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k]], [[6mft]], [[6mdt]], [[6mco]], [[6d2p]], [[6ck9]], [[6ch9]], [[6ch8]], [[6ch7]], [[6wix]] - Gp120 core + Gp41 + antibody<br />
-
**[[6ccb]], [[6x5b]], [[6x9r]], [[6x9s]], [[6x9t]], [[6x9u]], [[6x9v]] - Gp120 29-504 (mutant) + Gp41 + antibody<br />
+
**[[6ccb]], [[6x5b]], [[6x9r]], [[6x9s]], [[6x9t]], [[6x9u]], [[6x9v]], [[6xrt]], [[7n65]], [[7pc2]], [[7rai]] - Gp120 29-504 (mutant) + Gp41 + antibody<br />
-
**[[5fyk]], [[5fyj]], [[4nco]], [[6nnj]], [[6nnf]], [[6nm6]] - Gp120 core (mutant) + Gp41 + antibody<br />
+
**[[6cde]], [[6cdi]], [[6okp]], [[6e5p]], [[6cuf]], [[6cue]], [[6chb]], [[5u1f]], [[5thr]], [[4cc8]], [[3j70]], [[6udj]], [[6udk]], [[6v8z]], [[6vlr]], [[6vo1]], [[6vtt]], [[7lo6]], [[7mxd]], [[7ugo]] - Gp120 core + Gp41 + antibody – Cryo EM<br />
-
**[[6cde]], [[6cdi]], [[6okp]], [[6e5p]], [[6cuf]], [[6cue]], [[6chb]], [[5u1f]], [[5thr]], [[4cc8]], [[3j70]], [[6u59]], [[6uda]], [[6udk]], [[6v8z]], [[6vlr]], [[6vo1]], [[6vtt]], [[7lo6]] - Gp120 core + Gp41 + antibody – Cryo EM<br />
+
**[[6mn7]], [[6nqd]], [[6olp]], [[6orn]], [[6oro]], [[6orp]], [[6orq]], [[6osy]], [[6pw6]], [[6u59]], [[6uda]], [[6ulc]], [[6um6]], [[6um7]], [[6v8x]], [[6vi0]], [[6vo0]], [[6vo3]], [[6vtt]], [[6vy2]], [[7l86]], [[7l87]], [[7l88]], [[7l89]], [[7l8a]], [[7l8b]], [[7l8c]], [[7l8d]], [[7l8s]], [[7l8t]], [[7l8u]], [[7l8w]], [[7l8x]], [[7l8y]], [[7l8z]], [[7l90]], [[7ll1]], [[7ll2]], [[7llk]], [[7lua]] - Gp120 29-508 + Gp41 + antibody – Cryo EM<br />
-
**[[6mn7]], [[6nqd]], [[6olp]], [[6orn]], [[6oro]], [[6orp]], [[6orq]], [[6pw6]], [[6u59]], [[6uda]], [[6ulc]], [[6um6]], [[6um7]], [[6v8x]], [[6vi0]], [[6vo0]], [[6vo3]], [[6vtt]], [[6vy2]], [[7l86]], [[7l87]], [[7l88]], [[7l89]], [[7l8a]], [[7l8b]], [[7l8c]], [[7l8d]], [[7l8s]], [[7l8t]], [[7l8u]], [[7l8w]], [[7l8x]], [[7l8y]], [[7l8z]], [[7l90]], [[7ll1]], [[7ll2]], [[7llk]], [[7lua]] - Gp120 29-508 + Gp41 + antibody – Cryo EM<br />
+
**[[6nc2]], [[6nc3]] - Gp120 29-508 (mutant) + Gp41 + antibody – Cryo EM<br />
**[[6nc2]], [[6nc3]] - Gp120 29-508 (mutant) + Gp41 + antibody – Cryo EM<br />
 +
**[[5fyk]], [[5fyj]], [[4nco]], [[6nnj]], [[6nnf]], [[6nm6]] - Gp120 core (mutant) + Gp41 + antibody<br />
**[[3j5m]] - Gp120 core (mutant) + Gp41 + antibody – Cryo EM<br />
**[[3j5m]] - Gp120 core (mutant) + Gp41 + antibody – Cryo EM<br />
-
**[[6u0n]] - Gp120 32-505 + Gp41 + antibody + CD4 – Cryo EM<br />
+
**[[6u0l]], [[6u0n]], [[8d5c]] - Gp120 32-505 + Gp41 + antibody + CD4 – Cryo EM<br />
**[[6um5]] - Gp120 30-489 + Gp41 + antibody + CH848 – Cryo EM<br />
**[[6um5]] - Gp120 30-489 + Gp41 + antibody + CH848 – Cryo EM<br />
**[[6vpx]], [[7lok]] - Gp120 core + Gp41 + antibody + peptide – Cryo EM<br />
**[[6vpx]], [[7lok]] - Gp120 core + Gp41 + antibody + peptide – Cryo EM<br />
 +
**[[7txd]] – Gp120 core + Gp41 + darpin + CD4 – Cryo EM<br />
 +
**[[8y6v]] – Gp120 in capsid – PhiKZ virus – Cryo EM<br />
 +
*Gp120 from HIV-2 binary complex
*Gp120 from HIV-2 binary complex
Line 66: Line 90:
**[[2bf1]], [[3fus]] - Gp120 core<br />
**[[2bf1]], [[3fus]] - Gp120 core<br />
**[[3jcc]], [[3jcb]] - Gp120 core + CD4 + antibody – Cryo EM<br />
**[[3jcc]], [[3jcb]] - Gp120 core + CD4 + antibody – Cryo EM<br />
 +
**[[7t2p]], [[7t4g]], [[8dua]] - Gp120 + Gp41 core + antibody – Cryo EM<br />
 +
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D structures of Gp120

Updated on 30-July-2025


Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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