7ruo
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human UTP15== | |
| - | + | <StructureSection load='7ruo' size='340' side='right'caption='[[7ruo]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7ruo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RUO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ruo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ruo OCA], [https://pdbe.org/7ruo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ruo RCSB], [https://www.ebi.ac.uk/pdbsum/7ruo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ruo ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/UTP15_HUMAN UTP15_HUMAN] Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I (PubMed:17699751). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).<ref>PMID:17699751</ref> <ref>PMID:34516797</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Zeng | + | [[Category: Large Structures]] |
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Dehghani-Tafti S]] | ||
| + | [[Category: Dong A]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Halabelian L]] | ||
| + | [[Category: Hutchinson A]] | ||
| + | [[Category: Loppnau P]] | ||
| + | [[Category: Seitova A]] | ||
| + | [[Category: Zeng H]] | ||
Current revision
Crystal structure of human UTP15
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