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7v63
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of dimeric uPAR at low pH== | |
| - | + | <StructureSection load='7v63' size='340' side='right'caption='[[7v63]], [[Resolution|resolution]] 2.91Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7v63]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7V63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7V63 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7v63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7v63 OCA], [https://pdbe.org/7v63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7v63 RCSB], [https://www.ebi.ac.uk/pdbsum/7v63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7v63 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/UPAR_HUMAN UPAR_HUMAN]] Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Huang, M]] | ||
| + | [[Category: Yuan, C]] | ||
| + | [[Category: Gpi-anchored protein]] | ||
| + | [[Category: Immune system]] | ||
Current revision
Structure of dimeric uPAR at low pH
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