1mvj

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==N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA NMR, 15 STRUCTURES==
==N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA NMR, 15 STRUCTURES==
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<StructureSection load='1mvj' size='340' side='right'caption='[[1mvj]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
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<StructureSection load='1mvj' size='340' side='right'caption='[[1mvj]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1mvj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Const Const]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MVJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MVJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1mvj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Conus_striatus Conus striatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MVJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MVJ FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 15 models</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mvj OCA], [https://pdbe.org/1mvj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mvj RCSB], [https://www.ebi.ac.uk/pdbsum/1mvj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mvj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mvj OCA], [https://pdbe.org/1mvj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mvj RCSB], [https://www.ebi.ac.uk/pdbsum/1mvj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mvj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CO16B_CONST CO16B_CONST]] Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav). This toxin blocks N-, P- and Q-type calcium channels.
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[https://www.uniprot.org/uniprot/O16B_CONST O16B_CONST] Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav). This toxin blocks N-, P- and Q-type calcium channels.<ref>PMID:1390774</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Const]]
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[[Category: Conus striatus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Alewood, P F]]
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[[Category: Alewood PF]]
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[[Category: Craik, D J]]
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[[Category: Craik DJ]]
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[[Category: Lewis, R J]]
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[[Category: Lewis RJ]]
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[[Category: Nielsen, K J]]
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[[Category: Nielsen KJ]]
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[[Category: Thomas, L]]
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[[Category: Thomas L]]
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[[Category: Conus striatus peptide specific to p/q-type voltage sensitive calcium channel]]
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[[Category: Neurotoxin]]
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N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA NMR, 15 STRUCTURES

PDB ID 1mvj

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