1mwu

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Current revision (08:39, 6 November 2024) (edit) (undo)
 
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<StructureSection load='1mwu' size='340' side='right'caption='[[1mwu]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='1mwu' size='340' side='right'caption='[[1mwu]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1mwu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MWU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1mwu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MWU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7EP:(2R,4S)-2-[(1R)-1-{[(2,6-DIMETHOXYPHENYL)CARBONYL]AMINO}-2-OXOETHYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>7EP</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1mwr|1mwr]], [[1mws|1mws]], [[1mwt|1mwt]], [[1mwx|1mwx]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7EP:(2R,4S)-2-[(1R)-1-{[(2,6-DIMETHOXYPHENYL)CARBONYL]AMINO}-2-OXOETHYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>7EP</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mwu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mwu OCA], [https://pdbe.org/1mwu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mwu RCSB], [https://www.ebi.ac.uk/pdbsum/1mwu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mwu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mwu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mwu OCA], [https://pdbe.org/1mwu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mwu RCSB], [https://www.ebi.ac.uk/pdbsum/1mwu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mwu ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q93IC2_STAAU Q93IC2_STAAU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mw/1mwu_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mw/1mwu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lim, D C]]
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[[Category: Staphylococcus aureus]]
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[[Category: Strynadka, N C.J]]
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[[Category: Lim DC]]
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[[Category: Beta-lactam]]
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[[Category: Strynadka NCJ]]
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[[Category: Biosynthetic protein]]
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[[Category: D-carboxypeptidase]]
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[[Category: D-transpeptidase]]
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[[Category: Methicillin]]
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[[Category: Penicillin binding protein]]
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Current revision

Structure of methicillin acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.60 A resolution.

PDB ID 1mwu

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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