7v5s

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'''Unreleased structure'''
 
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The entry 7v5s is ON HOLD until Paper Publication
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==Crystal structure of human bleomycin hydrolase C73A mutant==
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<StructureSection load='7v5s' size='340' side='right'caption='[[7v5s]], [[Resolution|resolution]] 3.02&Aring;' scene=''>
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Authors: Chang, C.Y., Zheng, Y.Z., Huang, S.J., Wang, Y.L., Toh, S.I., Lin, E.C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7v5s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7V5S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7V5S FirstGlance]. <br>
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Description: Crystal structure of human bleomycin hydrolase C73A mutant
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.02&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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[[Category: Chang, C.Y]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7v5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7v5s OCA], [https://pdbe.org/7v5s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7v5s RCSB], [https://www.ebi.ac.uk/pdbsum/7v5s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7v5s ProSAT]</span></td></tr>
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[[Category: Lin, E.C]]
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</table>
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[[Category: Zheng, Y.Z]]
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== Function ==
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[[Category: Toh, S.I]]
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[https://www.uniprot.org/uniprot/BLMH_HUMAN BLMH_HUMAN] The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity).
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[[Category: Huang, S.J]]
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__TOC__
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[[Category: Wang, Y.L]]
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chang CY]]
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[[Category: Huang SJ]]
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[[Category: Lin EC]]
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[[Category: Toh SI]]
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[[Category: Wang YL]]
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[[Category: Zheng YZ]]

Current revision

Crystal structure of human bleomycin hydrolase C73A mutant

PDB ID 7v5s

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OCA

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