7s3o
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==NMR Solution Structure of hGal(2-12)KK, a solubility-tagged truncation of the human neuropeptide galanin== | |
| - | + | <StructureSection load='7s3o' size='340' side='right'caption='[[7s3o]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7s3o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7S3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7S3O FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7s3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7s3o OCA], [https://pdbe.org/7s3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7s3o RCSB], [https://www.ebi.ac.uk/pdbsum/7s3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7s3o ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [[https://www.uniprot.org/uniprot/GALA_HUMAN GALA_HUMAN]] The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/GALA_HUMAN GALA_HUMAN]] Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.<ref>PMID:1370155</ref> <ref>PMID:1722333</ref> <ref>PMID:25691535</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Clinkscales SE]] | ||
| + | [[Category: Giuliano MW]] | ||
| + | [[Category: Kraichely KN]] | ||
| + | [[Category: Parnham S]] | ||
Current revision
NMR Solution Structure of hGal(2-12)KK, a solubility-tagged truncation of the human neuropeptide galanin
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