7byi
From Proteopedia
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| - | ==== | + | ==Structure of SHMT2 in complex with CBX== |
| - | <StructureSection load='7byi' size='340' side='right'caption='[[7byi]]' scene=''> | + | <StructureSection load='7byi' size='340' side='right'caption='[[7byi]], [[Resolution|resolution]] 2.76Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7byi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BYI FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7byi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7byi OCA], [https://pdbe.org/7byi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7byi RCSB], [https://www.ebi.ac.uk/pdbsum/7byi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7byi ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.76Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBO:CARBENOXOLONE'>CBO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7byi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7byi OCA], [https://pdbe.org/7byi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7byi RCSB], [https://www.ebi.ac.uk/pdbsum/7byi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7byi ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GLYM_HUMAN GLYM_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.<ref>PMID:21876188</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Serine hydroxymethyltransferase 3D structures|Serine hydroxymethyltransferase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Chen Y]] |
| + | [[Category: Li L]] | ||
| + | [[Category: Lu D]] | ||
| + | [[Category: Su D]] | ||
| + | [[Category: Zhang C]] | ||
Current revision
Structure of SHMT2 in complex with CBX
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Categories: Homo sapiens | Large Structures | Chen Y | Li L | Lu D | Su D | Zhang C
