1rl6

From Proteopedia

(Difference between revisions)

Current revision

RIBOSOMAL PROTEIN L6

Structural highlights

1rl6 is a 1 chain structure with sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RL6_GEOSE It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity). This protein binds to the 23S rRNA, and is important in its secondary structure.[HAMAP-Rule:MF_01365]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

In all cells, protein synthesis is coordinated by the ribosome, a large ribonucleoprotein particle that is composed of > 50 distinct protein molecules and several large RNA molecules. Here we present the crystal structure of ribosomal protein L6 from the thermophilic bacterium Bacillus stearothermophilus solved at 2.6 A resolution. L6 contains two domains with almost identical folds, implying that it was created by an ancient gene duplication event. The surface of the molecule displays several likely sites of interaction with other components of the ribosome. The RNA binding sites appear to be localized in the C-terminal domain whereas the N-terminal domain contains the potential sites for protein-protein interactions. The domain structure is homologous with several other ribosomal proteins and to a large family of eukaryotic RNA binding proteins.

Ribosomal protein L6: structural evidence of gene duplication from a primitive RNA binding protein.,Golden BL, Ramakrishnan V, White SW EMBO J. 1993 Dec 15;12(13):4901-8. PMID:8262035^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Golden BL, Ramakrishnan V, White SW. Ribosomal protein L6: structural evidence of gene duplication from a primitive RNA binding protein. EMBO J. 1993 Dec 15;12(13):4901-8. PMID:8262035

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 See Also
6 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1rl6"

@@ Line 3: / Line 3: @@
 <StructureSection load='1rl6' size='340' side='right'caption='[[1rl6]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1rl6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RL6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RL6 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1rl6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RL6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RL6 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rl6 OCA], [https://pdbe.org/1rl6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rl6 RCSB], [https://www.ebi.ac.uk/pdbsum/1rl6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rl6 ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rl6 OCA], [https://pdbe.org/1rl6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rl6 RCSB], [https://www.ebi.ac.uk/pdbsum/1rl6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rl6 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/RL6_GEOSE RL6_GEOSE]] It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity). This protein binds to the 23S rRNA, and is important in its secondary structure.[HAMAP-Rule:MF_01365]
+[https://www.uniprot.org/uniprot/RL6_GEOSE RL6_GEOSE] It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity). This protein binds to the 23S rRNA, and is important in its secondary structure.[HAMAP-Rule:MF_01365]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 34: / Line 35: @@
 __TOC__
 </StructureSection>
-[[Category: Atcc 12980]]
+[[Category: Geobacillus stearothermophilus]]
 [[Category: Large Structures]]
-[[Category: Davies, C]]
+[[Category: Davies C]]
-[[Category: Golden, B L]]
+[[Category: Golden BL]]
-[[Category: Ramakrishnan, V]]
+[[Category: Ramakrishnan V]]
-[[Category: White, S W]]
+[[Category: White SW]]
-[[Category: Alpha/beta protein]]
-[[Category: Gentamicin resistance]]
-[[Category: Ribosomal protein]]
-[[Category: Rna binding protein]]
-[[Category: Rna-binding protein]]

1rl6

From Proteopedia

Current revision

RIBOSOMAL PROTEIN L6

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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