1s2r
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 4: | Line 4: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1s2r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S2R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S2R FirstGlance]. <br> | <table><tr><td colspan='2'>[[1s2r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S2R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S2R FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s2r OCA], [https://pdbe.org/1s2r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s2r RCSB], [https://www.ebi.ac.uk/pdbsum/1s2r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s2r ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s2r OCA], [https://pdbe.org/1s2r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s2r RCSB], [https://www.ebi.ac.uk/pdbsum/1s2r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s2r ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The crystal structure of [d(CGCAAATTTGCG)]2 has been determined to 1.5 A resolution, representing the first high-resolution structure of this DNA fragment. The ion interactions are novel. A spermine molecule replaces a Mg2+ observed in analogous structures. Unlike lower-resolution structures, the minor groove is narrow and the major groove lacks extra Watson-Crick hydrogen bonds. In addition, a monolayer of solvent sites, including a "spine of hydration", is visible in the minor groove. The crystal of [d(CGCAAATTTGCG)]2 was grown from a solution containing spermine, magnesium, and lithium. The conformation recapitulates that of "monovalent-minus" DNA. | ||
| - | |||
| - | High-resolution structure of an extended A-tract: [d(CGCAAATTTGCG)]2.,Woods KK, Maehigashi T, Howerton SB, Sines CC, Tannenbaum S, Williams LD J Am Chem Soc. 2004 Dec 1;126(47):15330-1. PMID:15563130<ref>PMID:15563130</ref> | ||
| - | |||
| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 1s2r" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Howerton | + | [[Category: Howerton SB]] |
| - | [[Category: Maehigashi | + | [[Category: Maehigashi T]] |
| - | [[Category: Tannenbaum | + | [[Category: Tannenbaum S]] |
| - | [[Category: Williams | + | [[Category: Williams LD]] |
| - | [[Category: Woods | + | [[Category: Woods KK]] |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
A High Resolution Crystal Structure of [d(CGCAAATTTGCG)]2
| |||||||||||
