1tf3

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==TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES==
==TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES==
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<StructureSection load='1tf3' size='340' side='right'caption='[[1tf3]], [[NMR_Ensembles_of_Models | 22 NMR models]]' scene=''>
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<StructureSection load='1tf3' size='340' side='right'caption='[[1tf3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1tf3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TF3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1tf3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TF3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tf3 OCA], [https://pdbe.org/1tf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tf3 RCSB], [https://www.ebi.ac.uk/pdbsum/1tf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tf3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tf3 OCA], [https://pdbe.org/1tf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tf3 RCSB], [https://www.ebi.ac.uk/pdbsum/1tf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tf3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TF3A_XENLA TF3A_XENLA]] Acts as both a positive transcription factor for 5S RNA genes and a specific RNA binding protein that complexes with 5S RNA in oocytes to form the 7S ribonucleoprotein storage particle. May play an essential role in the developmental change in 5S RNA gene expression. Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's.
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[https://www.uniprot.org/uniprot/TF3A_XENLA TF3A_XENLA] Acts as both a positive transcription factor for 5S RNA genes and a specific RNA binding protein that complexes with 5S RNA in oocytes to form the 7S ribonucleoprotein storage particle. May play an essential role in the developmental change in 5S RNA gene expression. Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: African clawed frog]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Case, D A]]
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[[Category: Xenopus laevis]]
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[[Category: Foster, M P]]
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[[Category: Case DA]]
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[[Category: Gottesfeld, J M]]
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[[Category: Foster MP]]
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[[Category: Radhakrishnan, I]]
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[[Category: Gottesfeld JM]]
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[[Category: Wright, P E]]
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[[Category: Radhakrishnan I]]
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[[Category: Wuttke, D S]]
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[[Category: Wright PE]]
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[[Category: 5s rna gene]]
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[[Category: Wuttke DS]]
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[[Category: Dna]]
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[[Category: Dna binding protein]]
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[[Category: Protein]]
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[[Category: Tfiiia]]
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[[Category: Transcription factor]]
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[[Category: Transcription-dna complex]]
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[[Category: Zinc finger]]
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Current revision

TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES

PDB ID 1tf3

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