1u3f
From Proteopedia
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<StructureSection load='1u3f' size='340' side='right'caption='[[1u3f]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='1u3f' size='340' side='right'caption='[[1u3f]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1u3f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1u3f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U3F FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u3f OCA], [https://pdbe.org/1u3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u3f RCSB], [https://www.ebi.ac.uk/pdbsum/1u3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u3f ProSAT], [https://www.topsan.org/Proteins/BSGC/1u3f TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u3f OCA], [https://pdbe.org/1u3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u3f RCSB], [https://www.ebi.ac.uk/pdbsum/1u3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u3f ProSAT], [https://www.topsan.org/Proteins/BSGC/1u3f TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MTHFS_MYCPN MTHFS_MYCPN] Involved in folate metabolism. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.<ref>PMID:16104022</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u3/1u3f_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u3/1u3f_consurf.spt"</scriptWhenChecked> | ||
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u3f ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u3f ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Filterable agent of primary atypical pneumonia eaton et al. 1944]] | ||
| - | [[Category: 5-formyltetrahydrofolate cyclo-ligase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Chen, S]] | ||
| - | [[Category: Kim, R]] | ||
| - | [[Category: Kim, S H]] | ||
| - | [[Category: Proudfoot, M]] | ||
| - | [[Category: Yakunin, A F]] | ||
| - | [[Category: 10-methenyltetrahydrofolate synthetase]] | ||
| - | [[Category: Atp binding]] | ||
| - | [[Category: Bsgc structure funded by nih]] | ||
| - | [[Category: Ligase]] | ||
| - | [[Category: Mthf]] | ||
[[Category: Mycoplasma pneumoniae]] | [[Category: Mycoplasma pneumoniae]] | ||
| - | [[Category: | + | [[Category: Chen S]] |
| + | [[Category: Kim R]] | ||
| + | [[Category: Kim S-H]] | ||
| + | [[Category: Proudfoot M]] | ||
| + | [[Category: Yakunin AF]] | ||
Current revision
Structural and Functional Characterization of a 5,10-Methenyltetrahydrofolate Synthetase from Mycoplasma pneumoniae (GI: 13508087)
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