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1urx

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Current revision (12:56, 13 December 2023) (edit) (undo)
 
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<StructureSection load='1urx' size='340' side='right'caption='[[1urx]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='1urx' size='340' side='right'caption='[[1urx]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1urx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"cytophaga_drobachiensis"_barbeyron_et_al._1998 "cytophaga drobachiensis" barbeyron et al. 1998]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1URX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1urx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zobellia_galactanivorans Zobellia galactanivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1URX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=AAL:3,6-ANHYDRO-L-GALACTOSE'>AAL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-agarase Beta-agarase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.81 3.2.1.81] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AAL:3,6-ANHYDRO-L-GALACTOSE'>AAL</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1urx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urx OCA], [https://pdbe.org/1urx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1urx RCSB], [https://www.ebi.ac.uk/pdbsum/1urx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1urx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1urx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urx OCA], [https://pdbe.org/1urx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1urx RCSB], [https://www.ebi.ac.uk/pdbsum/1urx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1urx ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AGAA_ZOBGA AGAA_ZOBGA] Cleaves the beta-1,4-linkages between beta-D-galactose and alpha-L-3,6-anhydro-galactose residues in agarose. Cleaves agarose in a random manner with retention of the anomeric-bond configuration, producing beta-anomers that give rise progressively to alpha-anomers when mutarotation takes place.<ref>PMID:15456406</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cytophaga drobachiensis barbeyron et al. 1998]]
 
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[[Category: Beta-agarase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Allouch, J]]
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[[Category: Zobellia galactanivorans]]
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[[Category: Czjzek, M]]
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[[Category: Allouch J]]
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[[Category: Helbert, W]]
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[[Category: Czjzek M]]
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[[Category: Henrissat, B]]
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[[Category: Helbert W]]
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[[Category: Agarose]]
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[[Category: Henrissat B]]
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[[Category: Double helix]]
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[[Category: Family 16]]
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[[Category: Glycoside hydrolase]]
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[[Category: Hydrolase]]
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[[Category: Two binding-site]]
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Current revision

Crystallographic structure of beta-agarase A in complex with oligoagarose

PDB ID 1urx

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