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Importin 3D structures

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Current revision (07:10, 29 May 2023) (edit) (undo)
 
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Line 7: Line 7:
**[[1ial]] – mIPO NLS-binding domain – mouse<br />
**[[1ial]] – mIPO NLS-binding domain – mouse<br />
-
**[[1bk5]] – yIPO NLS-binding domain - yeast<br />
+
**[[6d7m]] – mIPO (mutant)<br />
**[[4tnm]] – IPO armadillo repeat domain – ''Arabidopsis thaliana''<br />
**[[4tnm]] – IPO armadillo repeat domain – ''Arabidopsis thaliana''<br />
 +
**[[1bk5]] – yIPO NLS-binding domain - yeast<br />
 +
**[[7vps]] – NgIPO ARM domain 75-516 – ''Nakaceomyces glabratus''<br />
*''IPO-α complex with NLS peptide''
*''IPO-α complex with NLS peptide''
Line 25: Line 27:
**[[4rxh]] – NcIPO NLS-binding domain + SV40 large T antigen – ''Neurospora crassa''<br />
**[[4rxh]] – NcIPO NLS-binding domain + SV40 large T antigen – ''Neurospora crassa''<br />
**[[5vqi]] – NcIPO NLS-binding domain + NIT2<br />
**[[5vqi]] – NcIPO NLS-binding domain + NIT2<br />
 +
**[[7vpt]] – NgIPO ARM domain + Upc2<br />
*''IPO-α complex with protein''
*''IPO-α complex with protein''
Line 34: Line 37:
*IPO-α 1
*IPO-α 1
-
**[[3wpt]] – hIPO NLS-binding domain - human<br />
+
**[[3wpt]], [[8fzk]] – hIPO NLS-binding domain - human<br />
**[[4b8j]] – rIPO <br />
**[[4b8j]] – rIPO <br />
**[[6bvt]] – mIPO NLS-binding domain <br />
**[[6bvt]] – mIPO NLS-binding domain <br />
**[[4u5v]], [[4u5u]], [[4u5s]], [[4u5o]], [[4u5n]], [[4u5l]], [[4u58]], [[4u54]] – mIPO NLS-binding domain + inhibitor<br />
**[[4u5v]], [[4u5u]], [[4u5s]], [[4u5o]], [[4u5n]], [[4u5l]], [[4u58]], [[4u54]] – mIPO NLS-binding domain + inhibitor<br />
-
**[[7s1e]] – IPO – guinea pig<br />
+
**[[8g4j]] – IPO – guinea pig<br />
*''IPO-α 1 complex with NLS peptide''
*''IPO-α 1 complex with NLS peptide''
Line 47: Line 50:
**[[6bw1]] – hIPO NLS-binding domain + Hendra virus peptide<br />
**[[6bw1]] – hIPO NLS-binding domain + Hendra virus peptide<br />
**[[5w4e]], [[5w4f]], [[5w4g]] – hIPO NLS-binding domain + polymerase peptide<br />
**[[5w4e]], [[5w4f]], [[5w4g]] – hIPO NLS-binding domain + polymerase peptide<br />
 +
**[[7n9h]] – hIPO NLS-binding domain + TDP-43 peptide<br />
 +
**[[7cru]] – hIPO NLS-binding domain + hnRNPK peptide<br />
 +
**[[8he3]] – hIPO NLS-binding domain + HIF-1 peptide<br />
**[[7n8j]] – hIPO NLS-binding domain + BIMAX peptide<br />
**[[7n8j]] – hIPO NLS-binding domain + BIMAX peptide<br />
**[[5h43]] – hIPO NLS-binding domain + histone acetyltransferase KAT8<br />
**[[5h43]] – hIPO NLS-binding domain + histone acetyltransferase KAT8<br />
 +
**[[8gai]] – IPO NLS-binding domain + BIMAX peptide – guinea pig<br />
**[[4mz5]], [[4mz6]] – mIPO NLS-binding domain 70-528 + dUTPase<br />
**[[4mz5]], [[4mz6]] – mIPO NLS-binding domain 70-528 + dUTPase<br />
**[[4oih]] – mIPO NLS-binding domain + guanine nucleotide exchange factor SRM1<br />
**[[4oih]] – mIPO NLS-binding domain + guanine nucleotide exchange factor SRM1<br />
Line 58: Line 65:
**[[5ekg]], [[5ekf]], [[5e6q]] – mIPO NLS-binding domain + XPG2<br />
**[[5ekg]], [[5ekf]], [[5e6q]] – mIPO NLS-binding domain + XPG2<br />
**[[5d5k]] – mIPO NLS-binding domain + PARP 2<br />
**[[5d5k]] – mIPO NLS-binding domain + PARP 2<br />
-
**[[7l04]] – mIPO NLS-binding domain + adeno-associated virus<br />
+
**[[7l04]], [[8fk3]] – mIPO NLS-binding domain + adeno-associated virus<br />
**[[5ctt]] – mIPO NLS-binding domain + SART3/TIP110<br />
**[[5ctt]] – mIPO NLS-binding domain + SART3/TIP110<br />
**[[5b56]] – mIPO NLS-binding domain + HIV-1 VPR<br />
**[[5b56]] – mIPO NLS-binding domain + HIV-1 VPR<br />
Line 67: Line 74:
**[[6iu7]], [[6iua]] – mIPO NLS-binding domain + TP53-binding protein <br />
**[[6iu7]], [[6iua]] – mIPO NLS-binding domain + TP53-binding protein <br />
**[[5w41]] – mIPO NLS-binding domain + Zika virus peptide <br />
**[[5w41]] – mIPO NLS-binding domain + Zika virus peptide <br />
 +
**[[8fua]], [[8fuc]] – mIPO NLS-binding domain + Hendra virus peptide<br />
 +
**[[8ech]] – mIPO NLS-binding domain + tick-bourne encephalitis virus<br />
**[[5v5o]], [[5v5p]] – mIPO NLS-binding domain + influenza virus peptide <br />
**[[5v5o]], [[5v5p]] – mIPO NLS-binding domain + influenza virus peptide <br />
**[[5umz]] – mIPO NLS-binding domain + TNRC6A peptide <br />
**[[5umz]] – mIPO NLS-binding domain + TNRC6A peptide <br />
Line 78: Line 87:
**[[7jjm]], [[7jk7]] – mIPO NLS-binding domain + LSD1 peptide <br />
**[[7jjm]], [[7jk7]] – mIPO NLS-binding domain + LSD1 peptide <br />
**[[7jvo]] – mIPO NLS-binding domain + ACE2 peptide <br />
**[[7jvo]] – mIPO NLS-binding domain + ACE2 peptide <br />
 +
**[[8he0]] – mIPO NLS-binding domain + HIF-1 peptide<br />
**[[7rg4]], [[7rg5]] – mIPO NLS-binding domain + p50 peptide <br />
**[[7rg4]], [[7rg5]] – mIPO NLS-binding domain + p50 peptide <br />
**[[6wx7]] – mIPO NLS-binding domain + SOX2 peptide <br />
**[[6wx7]] – mIPO NLS-binding domain + SOX2 peptide <br />
Line 105: Line 115:
**[[1y2a]], [[3q5u]] – mIPO NLS-binding domain + phospholipid scramblase <br />
**[[1y2a]], [[3q5u]] – mIPO NLS-binding domain + phospholipid scramblase <br />
**[[2c1m]] – mIPO NLS-binding domain + Nup50<br />
**[[2c1m]] – mIPO NLS-binding domain + Nup50<br />
 +
**[[7leq]] – mIPO NLS-binding domain + p50<br />
 +
**[[7leu]] – mIPO NLS-binding domain + p65<br />
**[[3btr]] – mIPO NLS-binding domain + androgen receptor<br />
**[[3btr]] – mIPO NLS-binding domain + androgen receptor<br />
**[[3knd]] – mIPO NLS-binding domain + targeting protein for KXLP2<br />
**[[3knd]] – mIPO NLS-binding domain + targeting protein for KXLP2<br />
Line 113: Line 125:
**[[3tpm]] – mIPO NLS-binding domain + MAL<br />
**[[3tpm]] – mIPO NLS-binding domain + MAL<br />
**[[3ve6]] – mIPO NLS-binding domain + Venezuelan equine encephalitis virus<br />
**[[3ve6]] – mIPO NLS-binding domain + Venezuelan equine encephalitis virus<br />
 +
**[[8f2q]] – mIPO NLS-binding domain + parvovirus<br />
**[[3uvu]] – mIPO NLS-binding domain + flap endonuclease<br />
**[[3uvu]] – mIPO NLS-binding domain + flap endonuclease<br />
**[[3ukw]], [[3ukx]] – mIPO NLS-binding domain + BIMAX<br />
**[[3ukw]], [[3ukx]] – mIPO NLS-binding domain + BIMAX<br />
Line 135: Line 148:
**[[6bvv]] – hIPO NLS-binding domain + Nipa virus peptide<br />
**[[6bvv]] – hIPO NLS-binding domain + Nipa virus peptide<br />
**[[5xzx]] – hIPO NLS-binding domain + RAN-binding protein peptide<br />
**[[5xzx]] – hIPO NLS-binding domain + RAN-binding protein peptide<br />
 +
**[[8hkw]] – hIPO NLS-binding domain + 53BP1 peptide<br />
**[[5tbk]] – hIPO NLS-binding domain + regulator of chromosome condensation <br />
**[[5tbk]] – hIPO NLS-binding domain + regulator of chromosome condensation <br />
**[[7rfy]] – hIPO + ORF4b<br />
**[[7rfy]] – hIPO + ORF4b<br />
**[[6wx8]] – hIPO + SOX2<br />
**[[6wx8]] – hIPO + SOX2<br />
 +
**[[7lfc]] – hIPO + p50 NLS<br />
 +
**[[7lf4]] – hIPO + p50 NLS + p65 NLS<br />
 +
**[[8fub]] – hIPO NLS-binding domain + Hendra virus peptide<br />
 +
**[[8fzm]] – mIPO NLS-binding domain + BIMAX<br />
 +
**[[7let]] – mIPO + p50 NLS + p65 NLS<br />
*IPO-α 5
*IPO-α 5
Line 149: Line 168:
*IPO-α 7
*IPO-α 7
 +
**[[7rht]] – hIPO <br />
**[[4uad]] – hIPO NLS-binding domain + influenza RNA polymerase<br />
**[[4uad]] – hIPO NLS-binding domain + influenza RNA polymerase<br />
*IPO-β
*IPO-β
-
**[[4xrk]] – IPO – ''Chaetomium thermophilum'' <br />
+
**[[4xri]], [[4xrk]] – IPO – ''Chaetomium thermophilum'' <br />
*IPO-β 1 (karyopherin β 1)
*IPO-β 1 (karyopherin β 1)
Line 207: Line 227:
**[[7jjl]] – hIPO + LSD1 peptide <br />
**[[7jjl]] – hIPO + LSD1 peptide <br />
 +
 +
*IPO-4
 +
 +
**[[8dyo]] – hIPO + RanGTP – Cryo EM<br />
 +
**[[7unk]] – hIPO + H3 + H4 + ASF1 – Cryo EM<br />
*IPO-4B
*IPO-4B
Line 230: Line 255:
**[[4c0o]] – hIPO + serine/arginine-rich splicing factor<br />
**[[4c0o]] – hIPO + serine/arginine-rich splicing factor<br />
**[[4c0q]], [[4ol0]] – hIPO + GTPase Ran<br />
**[[4c0q]], [[4ol0]] – hIPO + GTPase Ran<br />
 +
**[[6gx9]] – hIPO + CPSF 68<br />
*IPO-13 (karyopherin 13)
*IPO-13 (karyopherin 13)

Current revision

3D structures of importin

Updated on 29-May-2023

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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