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7sbf
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7sbf is ON HOLD Authors: Huang, W., Qu, Q., Wang, H., Kobilka, B. Description: PZM21 bound Mu Opioid Receptor-Gi Protein Complex [[Category: Unrele...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==PZM21 bound Mu Opioid Receptor-Gi Protein Complex== | |
| + | <StructureSection load='7sbf' size='340' side='right'caption='[[7sbf]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7sbf]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SBF FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8QY:N-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-N-[(2S)-1-(thiophen-3-yl)propan-2-yl]urea'>8QY</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sbf OCA], [https://pdbe.org/7sbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sbf RCSB], [https://www.ebi.ac.uk/pdbsum/7sbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sbf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Transducin 3D structures|Transducin 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Huang | + | __TOC__ |
| - | [[Category: Qu | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia coli]] |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Huang W]] | ||
| + | [[Category: Kobilka B]] | ||
| + | [[Category: Qu Q]] | ||
| + | [[Category: Skiniotis G]] | ||
| + | [[Category: Wang H]] | ||
Current revision
PZM21 bound Mu Opioid Receptor-Gi Protein Complex
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Categories: Escherichia coli | Homo sapiens | Large Structures | Mus musculus | Huang W | Kobilka B | Qu Q | Skiniotis G | Wang H
