7vkr
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of D. melanogaster SAMTOR in complex with SAM== | |
| - | + | <StructureSection load='7vkr' size='340' side='right'caption='[[7vkr]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7vkr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VKR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vkr OCA], [https://pdbe.org/7vkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vkr RCSB], [https://www.ebi.ac.uk/pdbsum/7vkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vkr ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/SAMTR_DROME SAMTR_DROME]] S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling (PubMed:29123071). Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1 (PubMed:29123071). Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.[HAMAP-Rule:MF_03044]<ref>PMID:29123071</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Drosophila melanogaster]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ding J]] | ||
| + | [[Category: Tang X]] | ||
| + | [[Category: Zhang T]] | ||
Current revision
Crystal structure of D. melanogaster SAMTOR in complex with SAM
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