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Ion channels 3D structures

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Line 10: Line 10:
**[[2d46]] – hVDCC β 4a – human - NMR<br />
**[[2d46]] – hVDCC β 4a – human - NMR<br />
**[[6nq0]], [[6nq1]], [[6nq2]] – hTpc2 – Cryo EM <br />
**[[6nq0]], [[6nq1]], [[6nq2]] – hTpc2 – Cryo EM <br />
 +
**[[8if4]] – hCav alpha-2+delta-1 – Cryo EM <br />
 +
**[[8if3]] – hCav alpha-2+delta-1 + drug – Cryo EM <br />
**[[2f3y]], [[2f3z]], [[2be6]] – hCav1.2 α 1C subunit+calmodulin <br />
**[[2f3y]], [[2f3z]], [[2be6]] – hCav1.2 α 1C subunit+calmodulin <br />
**[[3oxq]] - hCav2.1 α 1C subunit IQ domain+hCalmodulin<br />
**[[3oxq]] - hCav2.1 α 1C subunit IQ domain+hCalmodulin<br />
**[[2vay]], [[3oxq]] - hCav1.1 α 1S subunit IQ domain+hCalmodulin<br />
**[[2vay]], [[3oxq]] - hCav1.1 α 1S subunit IQ domain+hCalmodulin<br />
 +
**[[8eoi]] – hCav1.2 in EMC chaperone – Cryo EM <br />
 +
**[[8fd7]] – hCav1.2 + drug – Cryo EM <br />
 +
**[[8eog]] – hCav1.2 + Leu – Cryo EM <br />
 +
**[[7uhg]] – hCav1.3 – Cryo EM <br />
 +
**[[7uhf]], [[8e59]], [[8e5a]], [[8e5b]] – hCav1.3 + drug – Cryo EM <br />
 +
**[[7vfs]] – hCav2.2 alpha-2+delta-1+beta1 – Cryo EM <br />
 +
**[[7vfu]], [[7vfv]], [[7vfw]] – hCav2.2 alpha-2+delta-1+beta1 + blocker – Cryo EM <br />
**[[7miy]] – hCav2.2C – Cryo EM <br />
**[[7miy]] – hCav2.2C – Cryo EM <br />
**[[7mix]] – hCav2.2C + conotoxin – Cryo EM <br />
**[[7mix]] – hCav2.2C + conotoxin – Cryo EM <br />
 +
**[[7xlq]], [[8epl]], [[8epm]] – hCav2.3 – Cryo EM <br />
**[[6kzo]] – hCav3.1C – Cryo EM <br />
**[[6kzo]] – hCav3.1C – Cryo EM <br />
**[[6kzp]] – hCav3.1C + antagonist – Cryo EM <br />
**[[6kzp]] – hCav3.1C + antagonist – Cryo EM <br />
-
**[[1hvd]], [[1hve]], [[1hvf]], [[1hvg]] – hAnnexin V (mutant)<br />
+
**[[7wli]] – hCav3.3 – Cryo EM <br />
 +
**[[7wlj]], [[7wlk]], [[7wll]] – hCav3.3 + drug – Cryo EM <br />
**[[6jp5]], [[6jp8]], [[7jpk]], [[7jpl]], [[7jpv]], [[7jpw]], [[7jpx]] – rCav1.1 – rabbit – Cryo EM<br />
**[[6jp5]], [[6jp8]], [[7jpk]], [[7jpl]], [[7jpv]], [[7jpw]], [[7jpx]] – rCav1.1 – rabbit – Cryo EM<br />
**[[6jpa]], [[6jpb]] – rCav1.1 + blocker – Cryo EM<br />
**[[6jpa]], [[6jpb]] – rCav1.1 + blocker – Cryo EM<br />
 +
**[[8e56]], [[8e57]], [[8e58]] – rCav1.1 + drug – Cryo EM<br />
**[[3bxx]] – rCav2.1 α 1A subunit+calmodulin - rabbit<br />
**[[3bxx]] – rCav2.1 α 1A subunit+calmodulin - rabbit<br />
**[[3bxl]] - rCav2.3 α 1E subunit+calmodulin<br />
**[[3bxl]] - rCav2.3 α 1E subunit+calmodulin<br />
Line 36: Line 48:
**[[5gjw]] – rCav1.1 α 2/δ 1 + α 1S + β 1 – Cryo EM<br />
**[[5gjw]] – rCav1.1 α 2/δ 1 + α 1S + β 1 – Cryo EM<br />
**[[5gjv]], [[3jbr]] – rCav1.1 α 2/δ 1 + α 1S + β 1 + γ 1 – Cryo EM<br />
**[[5gjv]], [[3jbr]] – rCav1.1 α 2/δ 1 + α 1S + β 1 + γ 1 – Cryo EM<br />
-
**[[5v2q]], [[5v2p]] - raCav1.2 1C + 2 - rat<br />
+
**[[5v2q]], [[5v2p]] - raCav1.2 alpha 1C + beta 2 - rat<br />
 +
**[[7qhh]] - raVDCC gamma 8 + glutamate receptor 1 – Cryo EM<br />
**[[5vov]], [[5vou]], [[5vot]], [[5kk2]] - raVDCC γ 2 + glutamate receptor 2 – Cryo EM<br />
**[[5vov]], [[5vou]], [[5vot]], [[5kk2]] - raVDCC γ 2 + glutamate receptor 2 – Cryo EM<br />
**[[6njl]], [[6njm]], [[6njn]] - raVDCC γ 2 + glutamate receptor 1 + glutamate receptor 2 + a’/c’ auxiliary protein + antibody – Cryo EM<br />
**[[6njl]], [[6njm]], [[6njn]] - raVDCC γ 2 + glutamate receptor 1 + glutamate receptor 2 + a’/c’ auxiliary protein + antibody – Cryo EM<br />
**[[6qkc]], [[6qkz]], [[7ocd]] - raVDCC γ 8 + glutamate receptor 1 + glutamate receptor 2 – Cryo EM<br />
**[[6qkc]], [[6qkz]], [[7ocd]] - raVDCC γ 8 + glutamate receptor 1 + glutamate receptor 2 – Cryo EM<br />
**[[7oca]], [[7oce]], [[7ocf]] - raVDCC γ 8 + glutamate receptor 1 + glutamate receptor 2 + CNIH-2 – Cryo EM<br />
**[[7oca]], [[7oce]], [[7ocf]] - raVDCC γ 8 + glutamate receptor 1 + glutamate receptor 2 + CNIH-2 – Cryo EM<br />
 +
**[[8e0e]] – raCav L-type 2 + nanobody<br />
**[[6c9a]], [[6c96]] – mTpc1 - mouse <br />
**[[6c9a]], [[6c96]] – mTpc1 - mouse <br />
**[[6c96]], [[6c9a]] – mTpc1 – Cryo EM <br />
**[[6c96]], [[6c9a]] – mTpc1 – Cryo EM <br />
**[[4zw2]] – mVDCC α 1S peptide + β 1 <br />
**[[4zw2]] – mVDCC α 1S peptide + β 1 <br />
**[[7lep]] - mVDCC γ 8 + glutamate receptor 2 + AMPAR subunits + CNIH-2 – Cryo EM<br />
**[[7lep]] - mVDCC γ 8 + glutamate receptor 2 + AMPAR subunits + CNIH-2 – Cryo EM<br />
-
**[[5tua]], [[5e1j]], [[5dqq]] – AtTpc1 – ''Arabidopsis thaliana'' <br />
+
**[[8dam]] – mCav L-type 1 + nanobody<br />
 +
**[[5tua]], [[5e1j]], [[5dqq]], [[7fhk]], [[7fhl]] – AtTpc1 – ''Arabidopsis thaliana'' <br />
**[[6cx0]] – AtTpc1 (mutant) <br />
**[[6cx0]] – AtTpc1 (mutant) <br />
-
**[[6e1m]], [[6e1n]], [[6e1p]] – AtTpc1 (mutant) – Cryo EM <br />
+
**[[6e1m]], [[6e1n]], [[6e1p]], [[7fhn]], [[7fho]], [[7tbg]], [[7tdd]], [[7tde]], [[7tdf]] – AtTpc1 (mutant) – Cryo EM <br />
**[[6e1k]] – AtTpc1 + antibody – Cryo EM <br />
**[[6e1k]] – AtTpc1 + antibody – Cryo EM <br />
**[[6mgv]], [[6mgw]], [[6ijz]] – AtOsca1.2 – Cryo EM <br />
**[[6mgv]], [[6mgw]], [[6ijz]] – AtOsca1.2 – Cryo EM <br />
 +
**[[4mtf]], [[4mtg]], [[4mto]] – AbCaV + Ca – ''Arcobacter butzleri''<br />
*See also [[Ryanodine receptor]]
*See also [[Ryanodine receptor]]
Line 55: Line 71:
*Sodium channel; Domains – extracellular 30-157
*Sodium channel; Domains – extracellular 30-157
-
**[[7dtd]] - hNaV 1.1 + hNav βγγ 4 – Cryo EM<br />
+
**[[7dtd]] - hNaV 1.1 + hNav beta 4 – Cryo EM<br />
-
**[[2kav]], [[2kbi]] - hNaV 1.2 α C-terminal EF-hand domain - NMR<br />
+
-
**[[5fdy]], [[5feb]] - hNaV 2 extracellular domain (mutant)<br />
+
**[[6agf]] - hNaV 1 + hNav 1.4 – Cryo EM<br />
**[[6agf]] - hNaV 1 + hNav 1.4 – Cryo EM<br />
-
**[[6j8e]] - hNaV 2 + hNav 1.2 + Mu-conotoxin – Cryo EM<br />
+
**[[2kav]], [[2kbi]] – hNaV 1.2 C-terminal EF-hand domain – NMR<br />
-
**[[6j8g]], [[6j8h]], [[6j8i]], [[6j8j]] - hNaV 2 + hNaV 1 + hNav 1.7 + toxin – Cryo EM<br />
+
**[[7w77]], [[7w7f]] – hNaV 1.3 beta1+beta2 + hNaV type 3 subunit alpha – Cryo EM<br />
 +
**[[5fdy]], [[5feb]] - hNaV 2 extracellular domain (mutant)<br />
**[[6vrr]] - hNaV 2 (mutant)<br />
**[[6vrr]] - hNaV 2 (mutant)<br />
-
**[[4l1d]] - hNaV β 3 extracellular domain <br />
+
**[[4l1d]] - hNaV 3 extracellular domain <br />
-
**[[4mz2]] - hNaV β 4 extracellular domain <br />
+
**[[4mz2]] - hNaV 4 extracellular domain <br />
-
**[[4mz3]], [[6vsv]] - hNaV β 4 extracellular domain (mutant)<br />
+
**[[4mz3]], [[6vsv]] - hNaV 4 extracellular domain (mutant)<br />
-
**[[6mba]], [[6mc9]] – hNaV 1.4 α C terminal + calmodulin <br />
+
**[[6bqn]] – hENaC alpha+beta+gamma subunits – Cryo EM<br />
-
**[[6bqn]] – hENaC α+β+γ subunits – Cryo EM<br />
+
**[[7dtc]] – hNaV 1.5 (mutant) – Cryo EM<br />
-
**[[6wth]] – hENAC α+β+γ subunits + antibody – Cryo EM<br />
+
**[[7l83]] – hNaV 1.5 1597-1633 - NMR <br />
-
**[[7dtc]] – hNaV 1.5 α (mutant) – Cryo EM<br />
+
**[[8fhd]] – hNaV 1.6 – Cryo EM<br />
-
**[[7l83]] – hNaV 1.5 α 1597-1633 - NMR <br />
+
**[[8gz1]] – hNaV 1.6 beta1+beta2 + hNaV type 8 subunit alpha – Cryo EM<br />
-
**[[6lqa]] – hNaV 1.5 α + quinidine - Cryo EM<br />
+
**[[7xvf]] – hNaV 1.7 (mutant) – Cryo EM<br />
-
**[[4ovn]], [[5dbr]], [[4djc]], [[6mud]] – hNaV 1.5 α C terminal + calmodulin <br />
+
**[[7w9l]], [[7w9t]] – hNaV 1.7 (mutant) + beta-1 + beta-2 – Cryo EM<br />
-
**[[4dck]], [[4jq0]] – hNaV 1.5 α C terminal + calmodulin + fibroblast growth factor <br />
+
**[[7w9k]] – hNaV 1.7 beta-1 + beta-2 – Cryo EM<br />
-
**[[4jpz]] – hNaV 1.2 α C terminal + calmodulin + fibroblast growth factor 13<br />
+
**[[7wfw]] – hNaV 1.8 – Cryo EM<br />
-
**[[1byy]] - rNaCh IIA inactivation fragment<br />
+
**[[7tj8]] – hNaV type 7 alpha – Cryo EM<br />
-
**[[5jr0]] – rNaV 1.4 α <br />
+
**[[7tj9]] – hNaV type 7 alpha + beta-3 – Cryo EM<br />
-
**[[6mue]] – raNaV 1.4 α + calmodulin <br />
+
**[[1byy]] – rNaCh IIA inactivation fragment<br />
-
**[[6uz3]] – raNaV 5 α - Cryo EM<br />
+
**[[5jr0]] – rNaV 1.4 <br />
-
**[[6uz0]] – raNaV 5 α + flecainide - Cryo EM<br />
+
**[[7fbs]] – raNaV 1.5 (mutant) – Cryo EM<br />
-
**[[7k18]] – raNaV 5 α + toxin - Cryo EM<br />
+
**[[6uz3]] – raNaV 5 - Cryo EM<br />
**[[1qg9]] – raNaCh IIA second repeat – NMR<br />
**[[1qg9]] – raNaCh IIA second repeat – NMR<br />
**[[5ayq]], [[5xax]], [[5xaw]] - mNaV 4 residues 30-160 <br />
**[[5ayq]], [[5xax]], [[5xaw]] - mNaV 4 residues 30-160 <br />
-
**[[5xsy]] – eeNaV 1.4 + β 1 – electric eel - Cryo EM <br />
+
**[[5xsy]] – eeNaV 1.4 + beta 1 – electric eel - Cryo EM <br />
**[[5x0m]] – coNaCh - cockroach <br />
**[[5x0m]] – coNaCh - cockroach <br />
-
**[[6a90]], [[6a91]], [[6a95]] – coNaCh + toxin – Cryo EM <br />
+
**[[4bgn]] – NaCh –'' Caldalkalibacillus thermarum'' – Cryo EM<br />
-
**[[4bgn]] – NaCh – ''Caldalkalibacillus thermarum'' – Cryo EM<br />
+
**[[4lto]], [[4ltp]], [[4ltq]], [[5hk7]] – AeNaCh pore + cytoplasmic domains – ''Alkalilimnicola ehrlichii'' <br />
**[[4lto]], [[4ltp]], [[4ltq]], [[5hk7]] – AeNaCh pore + cytoplasmic domains – ''Alkalilimnicola ehrlichii'' <br />
**[[4ltr]], [[5hkd]], [[5hk6]], [[5kj8]] – AeNaCh pore + cytoplasmic domains (mutant) <br />
**[[4ltr]], [[5hkd]], [[5hk6]], [[5kj8]] – AeNaCh pore + cytoplasmic domains (mutant) <br />
-
**[[5yua]] - AbNaVab – ''Arcobacter butzleri''<br />
+
**[[5iwn]], [[7pgh]] – AeNaCh pore domain<br />
-
**[[5yuc]], [[5yub]] - AbNaVab (mutant) <br />
+
**[[7x5v]] – NaV – Emiliania huxleyi - Cryo EM<br />
 +
 
 +
*Sodium channel complex
 +
 
 +
**[[6j8e]] - hNaV 2 + hNav 1.2 + Mu-conotoxin – Cryo EM<br />
 +
**[[6j8g]], [[6j8h]], [[6j8i]], [[6j8j]] - hNaV 2 + hNaV 1 + hNav 1.7 + toxin – Cryo EM<br />
 +
**[[6mba]], [[6mc9]] – hNaV 1.4 C terminal + calmodulin <br />
 +
**[[6wth]] – hENaC alpha+beta+gamma subunits + antibody – Cryo EM<br />
 +
**[[6lqa]] – hNaV 1.5 + quinidine - Cryo EM<br />
 +
**[[4ovn]], [[5dbr]], [[4djc]], [[6mud]] – hNaV 1.5 C terminal + calmodulin <br />
 +
**[[4dck]], [[4jq0]] – hNaV 1.5 C terminal + calmodulin + fibroblast growth factor <br />
 +
**[[4jpz]] – hNaV 1.2 C terminal + calmodulin + fibroblast growth factor 13<br />
 +
**[[8gz2]] – hNaV 1.6 beta1+beta2 + hNaV type 8 subunit alpha + toxin – Cryo EM<br />
 +
**[[7w9m]], [[7w9p]] – hNaV 1.7 beta1+beta2 + hNaV type 9 subunit alpha + toxin – Cryo EM<br />
 +
**[[7xm9]], [[7xmf]], [[7xmg]] – hNaV 1.7 beta1+beta2 + hNaV type 9 subunit alpha + inhibitor – Cryo EM<br />
 +
**[[7we4]], [[7wel]], [[7wfr]] – hNaV 1.8 + inhibitor – Cryo EM<br />
 +
**[[6mue]] – raNaV 1.4 + calmodulin <br />
 +
**[[6uz0]] – raNaV 5 + flecainide - Cryo EM<br />
 +
**[[7k18]] – raNaV 5 + toxin - Cryo EM<br />
 +
**[[6a90]], [[6a91]], [[6a95]] – coNaCh + toxin – Cryo EM <br />
 +
**[[7pg8]], [[7pgb]] – AeNaCh pore + antibody<br />
 +
 
 +
 
 +
*Sodium channel, pre-activated. NavAb
 +
 
 +
**[[4ekw]], [[4mw8]], [[5vb2]], [[5yua]], [[6mwa]] - AbNaVab – ''Arcobacter butzleri''<br />
 +
**[[3rvy]], [[3rvz]], [[3rw0]], [[5yuc]], [[5yub]], [[6c1e]], [[6c1m]], [[6mwb]], [[6mwd]], [[6mwg]], [[6p6w]], [[6p6x]], [[6p6y]] - AbNaVab (mutant) <br />
 +
**[[6mvv]], [[6mvy]] - AbNaVab (mutant) + lidocaine <br />
 +
**[[6ke5]] - AbNaVab + drug <br />
 +
 
 +
*Sodium channel, activated. NavMs
 +
 
 +
**[[3zjz]], [[4cbc]], [[4f4l]], [[4x89]], [[4x8a]], [[5bzb]], [[5hvx]] – MmNavMs – ''Magnetococcus marinus'' <br />
 +
**[[4x88]], [[5hvd]], [[6sx5]], [[6sx7]], [[6yz2]] – MmNavMs (mutant) <br />
 +
**[[4osx]], [[4p2z]], [[4p30]], [[4p9o]], [[4p9p]], [[4pa3]], [[4pa4]], [[4pa6]], [[4pa7]], [[4pa9]] – MmNavMs + blocker<br />
 +
**[[6sxg]] – MmNavMs + tamoxifen derivative<br />
 +
**[[6sxc]], [[6sxe]], [[6sxf]], [[6z8c]] – MmNavMs (mutant) + tamoxifen derivative<br />
 +
**[[6yz0]] – MmNavMs (mutant) + cannabidiol<br />
* NH4+ channel
* NH4+ channel
Line 103: Line 154:
**[[3hzq]] – MscL – ''Staphylococcus aureus''<br />
**[[3hzq]] – MscL – ''Staphylococcus aureus''<br />
-
**[[2oar]] – MscL – ''Mycobacterium tuberculosis''<br />
+
**[[2oar]], [[6ctd]] – MtMscL – ''Mycobacterium tuberculosis''<br />
**[[4lku]] – EcMscL C terminal<br />
**[[4lku]] – EcMscL C terminal<br />
-
**[[4y7k]], [[4y7j]] – MscL – Methanosarcina acetivorans<br />
+
**[[4y7k]], [[4y7j]] – MscL – ''Methanosarcina acetivorans''<br />
**[[2oau]], [[2vv5]], [[4hwa]] - EcMscS<br />
**[[2oau]], [[2vv5]], [[4hwa]] - EcMscS<br />
 +
**[[6pwn]], [[6pwo]], [[6pwp]], [[6rld]], [[6uzh]], [[6vyk]], [[6vyl]], [[6vym]], [[7onj]], [[7onl]], [[7oo0]], [[7oo6]], [[7oo8]], [[7ooa]] – EcMscS – Cryo EM<br />
**[[4age]], [[4agf]], [[5aji]] – EcMscS (mutant)<br />
**[[4age]], [[4agf]], [[5aji]] – EcMscS (mutant)<br />
**[[3t9n]], [[3udc]] – MscS – ''Thermoanaerobacter tengcongensis''<br />
**[[3t9n]], [[3udc]] – MscS – ''Thermoanaerobacter tengcongensis''<br />
Line 112: Line 164:
**[[6lyp]], [[6vxm]], [[6vxn]], [[6vxp]] – AtMsc-like (mutant) – Cryo EM<br />
**[[6lyp]], [[6vxm]], [[6vxn]], [[6vxp]] – AtMsc-like (mutant) – Cryo EM<br />
-
* Chloride channel
+
* Chloride channel or H(+)/Cl(-) exchange transporter ClcA or human proton-activated chloride channel PAC or CLIC
**[[1rk4]], [[3swl]] - hClCh protein 1<br />
**[[1rk4]], [[3swl]] - hClCh protein 1<br />
Line 126: Line 178:
**[[6y2h]] - hClCh protein 5<br />
**[[6y2h]] - hClCh protein 5<br />
**[[2j9l]], [[2ja3]] - hClCh protein 5 + nucleotide<br />
**[[2j9l]], [[2ja3]] - hClCh protein 5 + nucleotide<br />
 +
**[[7bxu]], [[7cq6]] - hClCh protein 7 + OSTM1 – Cryo EM<br />
 +
**[[7cq7]] - hClCh protein 7 + OSTM1 + ADP – Cryo EM<br />
 +
**[[7cq5]], [[7jm7]] - hClCh protein 7 + OSTM1 + ATP – Cryo EM<br />
 +
**[[7jna]], [[7jnc]] - hClCh PAC – Cryo EM<br />
**[[5tr1]], [[5tqq]] - bCIC (mutant) + antibody – bovine - Cryo EM<br />
**[[5tr1]], [[5tqq]] - bCIC (mutant) + antibody – bovine - Cryo EM<br />
**[[6erz]], [[6ery]] - mClCh protein 6<br />
**[[6erz]], [[6ery]] - mClCh protein 6<br />
-
**[[1ots]] - EcERIC + antibody<br />
+
**[[7jm6]] - cClCh protein 7 + ATP – chicken - Cryo EM<br />
-
**[[1ott]], [[1otu]] - EcERIC (mutant) + antibody<br />
+
**[[6lsc]], [[6v2j]] - EcERIC (mutant) <br />
 +
**[[1ots]], [[6k5f]] - EcERIC + antibody<br />
 +
**[[1ott]], [[1otu]], [[6ad7]], [[6ad8]], [[6ada]], [[6adb]], [[6adc]], [[6k5a]], [[6k5d]], [[7cvs]], [[7cvt]] - EcERIC (mutant) + antibody<br />
**[[2d4z]] - TmClCh - ''Torpedo marmorata''<br />
**[[2d4z]] - TmClCh - ''Torpedo marmorata''<br />
**[[2yv9]] - CeClCh EXC-4 – ''Caenorhabditis elegans''<br />
**[[2yv9]] - CeClCh EXC-4 – ''Caenorhabditis elegans''<br />
**[[3rif]] - CeClCh + antibody + Glu + Ivermectin<br />
**[[3rif]] - CeClCh + antibody + Glu + Ivermectin<br />
 +
**[[7ji3]] - CICh – ''Takifugu bimaculatus'' - Cryo EM<br />
**[[5y7i]] - ClCh – ''Oreochromis mossabicus''<br />
**[[5y7i]] - ClCh – ''Oreochromis mossabicus''<br />
 +
 +
*Calcium-activated chloride channel or anoctamin or scramblase see [[Anoctamin 3D structures]]
 +
 +
*Calcium-activated chloride channel or bestrophin see [[Bestrophin 3D structures]]
*CAMP-dependent chloride channel or cystic fibrosis transmembrane conductance regulator see CFTR in [[ABC transporter 3D structures]]
*CAMP-dependent chloride channel or cystic fibrosis transmembrane conductance regulator see CFTR in [[ABC transporter 3D structures]]
Line 141: Line 204:
**[[2jk4]], [[2k4t]], [[5jdp]], [[5xdo]], [[5xdn]], [[6g73]], [[6g6u]] – hVDAC1<br />
**[[2jk4]], [[2k4t]], [[5jdp]], [[5xdo]], [[5xdn]], [[6g73]], [[6g6u]] – hVDAC1<br />
**[[6tiq]] – hVDAC1 – NMR<br />
**[[6tiq]] – hVDAC1 – NMR<br />
 +
**[[7qi2]] – hVDAC1 (mutant) – NMR<br />
**[[6tir]] – hVDAC1 + NAD – NMR<br />
**[[6tir]] – hVDAC1 + NAD – NMR<br />
-
**[[6djb]], [[5zsu]] – hVDAC1 subunit LRRC8A – Cryo EM<br />
+
**[[6djb]], [[5zsu]], [[7xzh]] – hVDAC1 subunit LRRC8A – Cryo EM<br />
 +
**[[8dxn]], [[8dxo]], [[8dxp]], [[8dxq]], [[8dxr]] – hVDAC1 subunit LRRC8A + LRRC8C – Cryo EM<br />
**[[6m04]] – hVDAC1 subunit LRRC8AD (mutant) – Cryo EM<br />
**[[6m04]] – hVDAC1 subunit LRRC8AD (mutant) – Cryo EM<br />
-
**[[3emn]], [[4c69]] – mVDAC1 <br />
+
[[3emn]], [[4c69]] – mVDAC1 <br />
-
**[[6g9o]], [[6g9l]], [[6g8z]], [[6o00]], [[6nzz]], [[6nzw]] – mVDAC1 subunit LRRC8A – Cryo EM<br />
+
**[[7kuh]] – mVDAC – electron crystallography <br />
 +
**[[6g9o]], [[6g9l]], [[6g8z]], [[6o00]], [[6nzz]], [[6nzw]], [[7m17]], [[7m19]] – mVDAC1 subunit LRRC8A – Cryo EM<br />
 +
**[[8b40]] – mVDAC1 subunit LRRC8C – Cryo EM<br />
 +
**[[8ben]] – mVDAC1 subunit LRRC8C LRR domain – Cryo EM<br />
 +
**[[8b42]], [[8dr8]], [[8dra]], [[8dre]], [[8drk]], [[8drn]], [[8dro]], [[8drq]], [[8ds3]], [[8ds9]], [[8dsa]], [[8dxn]] – mVDAC1 subunit LRRC8A + LRRC8C – Cryo EM<br />
 +
**[[8f74]], [[8f75]], [[8f77]], [[8f79]], [[8f7b]], [[8f7d]], [[8f7e]], [[8f7j]] – mVDAC1 subunit LRRC8A + LRRC8C (mutant) – Cryo EM<br />
 +
**[[8b41]] – mVDAC1 subunit LRRC8A + LRRC8C + nanobody – Cryo EM<br />
 +
**[[7p5v]], [[7p5w]], [[7p5y]], [[7p60]], [[7p6k]] – mVDAC1 subunit LRRC8A + nanobody – Cryo EM<br />
**[[6fnw]] – mVDAC1 subunit LRRC8A C terminal<br />
**[[6fnw]] – mVDAC1 subunit LRRC8A C terminal<br />
-
**[[4bum]] – zeVDAC2 – zebra fish<br />
+
**[[4bum]] – zeVDAC2 <br />
 +
**[[7en0]] – VDAC1 – ''Brachypodium distachyon'' – Cryo EM<br />
 +
**[[7w6k]] – ALMT – soy bean – Cryo EM<br />
 +
**[[7wnq]] – AtSLAC1 – Cryo EM<br />
* Ligand-gated ion channel
* Ligand-gated ion channel
-
**[[2vl0]], [[2yn6]], [[3rqu]] – EchELIC – ''Erwinia chrysanthemi''<br />
+
**[[5osa]], [[5osb]] – mGLIC + GABAAR <br />
-
**[[2yks]], [[4twh]] - EchELIC (mutant)<br />
+
**[[5osc]] – mGLIC + GABAAR + drug<br />
 +
**[[2vl0]], [[3rqu]], [[2yn6]] – EchELIC –'' Erwinia chrysanthemi''<br />
 +
**[[2yks]], [[3uq4]], [[3uq5]], [[3uq7]], [[4twh]], [[5hej]], [[5heo]], [[5heu]], [[5hew]] – EchELIC (mutant)<br />
 +
**[[6v03]], [[6v0b]], [[8d63]], [[8d64]], [[8d65]] - EchELIC – Cryo EM<br />
 +
**[[8d66]], [[8d67]], [[8vuw]] – EchELIC3 (mutant) – Cryo EM<br />
**[[3rqw]] - EchELIC + acetylcholine<br />
**[[3rqw]] - EchELIC + acetylcholine<br />
 +
**[[5sxu]] - EchELIC + bromoethanol<br />
**[[4twd]], [[4twf]] - EchELIC (mutant) + memantine derivative<br />
**[[4twd]], [[4twf]] - EchELIC (mutant) + memantine derivative<br />
**[[3zkr]] - EchELIC + anesthetic<br />
**[[3zkr]] - EchELIC + anesthetic<br />
-
**[[4a97]], [[4a98]] – EchELIC + benzodiazepine<br />
+
**[[2yoe]] - EchELIC + drug + GABA<br />
-
**[[2yoe]] - EchELIC + flurazepam + GABA<br />
+
**[[4a97]], [[4a98]], [[5lid]], [[5lg3]] – EchELIC + drug<br />
-
**[[5lid]] – EchELIC + bromopromazine <br />
+
**[[5sxv]] – EchELIC + inhibitor <br />
**[[5sxv]] – EchELIC + inhibitor <br />
 +
**[[4yeu]] – EchELIC + GLIC <br />
 +
**[[6hk0]] – DcELIC (mutant) – Dickeya chrysanthemi<br />
 +
**[[6hjx]], [[6hjy]], [[6ssi]], [[6ssp]] – DcELIC + nanobody <br />
 +
**[[6fl9]], [[6fli]], [[6fvq]], [[6fvr]], [[6fvs]] - ELIC – vent tica<br />
 +
**[[3eam]], [[3ehz]], [[4hfi]], [[4il4]], [[4ilc]], [[4npp]], [[4npq]], [[4qh1]], [[4qh5]], [[4qh4]], [[6f7a]], [[6f16]], [[4zzc]], [[6hzw]] – GvGLIC - Gloeobacter violaceus<br />
 +
**[[6zgd]], [[6zgj]], [[6zgk]] – GvGLIC – Cryo EM<br />
**[[6hk0]] – DcELIC (mutant) – ''Dickeya chrysanthemi''<br />
**[[6hk0]] – DcELIC (mutant) – ''Dickeya chrysanthemi''<br />
**[[6hjx]], [[6hjy]], [[6ssi]], [[6ssp]] – DcELIC + nanobody <br />
**[[6hjx]], [[6hjy]], [[6ssi]], [[6ssp]] – DcELIC + nanobody <br />
Line 174: Line 259:
**[[5l47]], [[5l4e]], [[5l4h]] - GvGLIC + barbiturate<br />
**[[5l47]], [[5l4e]], [[5l4h]] - GvGLIC + barbiturate<br />
**[[6hj3]], [[6hjb]], [[6hji]], [[6hja]], [[6hjz]], [[6hpp]] - GvGLIC + carboxylate<br />
**[[6hj3]], [[6hjb]], [[6hji]], [[6hja]], [[6hjz]], [[6hpp]] - GvGLIC + carboxylate<br />
 +
**[[6v4a]], [[6v4s]], [[7q3g]] - DeELIC – ''Desulfofustis''<br />
 +
**[[7q3h]] – DeELIC – Cryo EM<br />
* Cyclic Nucleotide-Gated channel
* Cyclic Nucleotide-Gated channel
 +
**[[7lg1]] – hCNGA1 (mutant) – Cryo EM<br />
 +
**[[7lft]] – hCNGA1 + cGMP – Cryo EM<br />
 +
**[[7lfw]], [[7lfx]], [[7lfy]] – hCNGA1 (mutant) + cGMP – Cryo EM<br />
 +
**[[7rh9]], [[7rhl]] – hCNGA1 + CNGB1 – Cryo EM<br />
 +
**[[7rhg]], [[7rhh]], [[7rhi]], [[7rhj]], [[7rhk]] – hCNGA1 + CNGB1 + cGMP – Cryo EM<br />
 +
**[[8bx7]] – bCNGA1 + CNGB1 + cGMP – Cryo EM<br />
 +
**[[7rhs]] – hCNGA3 + CNGB3 – Cryo EM<br />
 +
**[[3swf]] - bCNGC CLZ domain <br />
**[[2zd9]], [[3beh]] - MlCNGC - ''Mesorhizobium loti''<br />
**[[2zd9]], [[3beh]] - MlCNGC - ''Mesorhizobium loti''<br />
**[[4chv]], [[4chw]] – MlCNGC – Cryo EM<br />
**[[4chv]], [[4chw]] – MlCNGC – Cryo EM<br />
Line 183: Line 278:
**[[3co2]], [[4muv]], [[3clp]], [[1u12]] - MlCNGC ligand-binding domain (mutant) <br />
**[[3co2]], [[4muv]], [[3clp]], [[1u12]] - MlCNGC ligand-binding domain (mutant) <br />
**[[3cl1]], [[2k0g]] - MlCNGC ligand-binding domain + cyclic nucleotide<br />
**[[3cl1]], [[2k0g]] - MlCNGC ligand-binding domain + cyclic nucleotide<br />
-
**[[3swf]] - CNGC CLZ domain - bovine<br />
 
**[[5h3o]] – CeCNGC – Cryo EM<br />
**[[5h3o]] – CeCNGC – Cryo EM<br />
 +
**[[6wej]], [[6wek]], [[6wel]] – CeCNGC + cGMP – Cryo EM<br />
 +
**[[6cju]], [[6vxz]], [[6vy0]] – StCNGC + cAMP – ''Spitochaeta thermophila'' - Cryo EM<br />
 +
**[[6cjq]] – StCNGC - Cryo EM<br />
 +
**[[6cjt]] – StCNGC + cGMP - Cryo EM<br />
*Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel
*Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel
-
**[[3etq]], [[3ffq]], [[3u0z]], [[3u10]], [[3u11]] - mCNGC C-terminal<br />
 
-
**[[1q3e]], [[1q43]], [[1q5o]] - mCNGC 2 fragment + nucleotide<br />
 
-
**[[2q0a]] - mCNGC 2 C-terminal (mutant)<br />
 
-
**[[3bpz]] - mCNGC 2 ligand-binding domain <br />
 
**[[5u6o]], [[5u6p]], [[6uqf]], [[6uqg]] – hCNGC 1 – Cryo EM<br />
**[[5u6o]], [[5u6p]], [[6uqf]], [[6uqg]] – hCNGC 1 – Cryo EM<br />
**[[2mpf]] – hCNGC 2 ligand-binding domain - NMR<br />
**[[2mpf]] – hCNGC 2 ligand-binding domain - NMR<br />
-
**[[5khg]], [[5khh]], [[5khi]], [[5khj]], [[5khk]] – mCNGC 2 ligand-binding domain + nucleotide<br />
 
**[[3swy]] – hCNGC 3 CLZ domain<br />
**[[3swy]] – hCNGC 3 CLZ domain<br />
**[[6gyn]] – hCNGC 4 – Cryo EM<br />
**[[6gyn]] – hCNGC 4 – Cryo EM<br />
Line 203: Line 296:
**[[4kl1]] – hCNGC 4 C terminal + nucleotide<br />
**[[4kl1]] – hCNGC 4 C terminal + nucleotide<br />
**[[4nvp]] – hCNGC 4 ligand-binding domain + 7-CH-cAMP<br />
**[[4nvp]] – hCNGC 4 ligand-binding domain + 7-CH-cAMP<br />
 +
**[[7nmn]], [[7np3]] – rCNGC 4 – Cryo EM<br />
 +
**[[7np4]] – rCNGC 4 + cAMP – Cryo EM<br />
 +
**[[3etq]], [[3ffq]], [[3u0z]], [[3u10]], [[3u11]] - mCNGC C-terminal<br />
 +
**[[1q3e]], [[1q43]], [[1q5o]] - mCNGC 2 fragment + nucleotide<br />
 +
**[[2q0a]] - mCNGC 2 C-terminal (mutant)<br />
 +
**[[3bpz]] - mCNGC 2 ligand-binding domain <br />
 +
**[[5khg]], [[5khh]], [[5khi]], [[5khj]], [[5khk]] – mCNGC 2 ligand-binding domain + nucleotide<br />
-
* Acid sensitive ion channel
+
* Acid sensing ion channel
 +
**[[6l6i]], [[6l6n]], [[6l6p]] – hASC <br />
 +
**[[7cfs]] – hASC – Cryo EM<br />
 +
**[[7cft]] – hASC + toxin – Cryo EM<br />
 +
**[[7rnn]] – hASC + nanobody – Cryo EM<br />
**[[3ij4]], [[2qts]], [[3s3w]], [[4nyk]], [[3ij4]], [[6ave]], [[5wku]], [[5wkv]], [[5wky]], [[5wkx]], [[6cmc]] – cASC – chicken<br />
**[[3ij4]], [[2qts]], [[3s3w]], [[4nyk]], [[3ij4]], [[6ave]], [[5wku]], [[5wkv]], [[5wky]], [[5wkx]], [[6cmc]] – cASC – chicken<br />
 +
**[[7lie]] – cASC thumb domain 291-367<br />
**[[6vtk]], [[6vtl]] – cASC – Cryo EM<br />
**[[6vtk]], [[6vtl]] – cASC – Cryo EM<br />
**[[3s3x]], [[4fz0]], [[4fz1]] – cASC + psalmotoxin<br />
**[[3s3x]], [[4fz0]], [[4fz1]] – cASC + psalmotoxin<br />
**[[4ntw]], [[4ntx]], [[4nty]] - cASC + neurotoxin + basic phospholipase A2<br />
**[[4ntw]], [[4ntx]], [[4nty]] - cASC + neurotoxin + basic phospholipase A2<br />
 +
**[[6x9h]] – cASC + modulator<br />
-
* ATP-Gated channel (AGC)
+
* ATP-Gated P2X channel (AGC) or P2X purinoceptor
-
**[[3h9v]], [[3i5d]] – zeAGC <br />
+
**[[5svj]], [[5svs]], [[5svt]] – hAGC P2X3 <br />
-
**[[4dw0]] – zeAGC (mutant)<br />
+
**[[5yve]] – hAGC P2X3 + modulator<br />
-
**[[4dw1]] – zeAGC + ATP<br />
+
**[[5svq]], [[5svr]] – hAGC P2X3 + antagonist<br />
 +
**[[5svm]], [[5svp]] – hAGC P2X3 + agonist<br />
 +
**[[5svk]], [[5svl]], [[6ah4]], [[6ah5]] – hAGC P2X3 + ATP<br />
 +
**[[5u1l]] – paAGC P2X - panda<br />
 +
**[[5u1u]], [[5u1v]], [[5u1w]], [[5u1x]], [[5u1y]] – paAGC P2X + antagonist <br />
 +
**[[5u2h]] – paAGC P2X + antagonist + ATP <br />
 +
**[[6u9v]] – raAGC P2X7 – Cryo EM<br />
 +
**[[6u9w]] – raAGC P2X7 + ATP – Cryo EM<br />
 +
**[[2rup]] – raAGC P2X4 head domain 111-167 – NMR<br />
 +
**[[5xw6]] – cAGC P2X7 + antagonist<br />
 +
**[[3h9v]], [[3i5d]] – zeAGC P2X4<br />
 +
**[[4dw0]] – zeAGC P2X4 (mutant)<br />
 +
**[[4dw1]] – zeAGC P2X4 + ATP<br />
 +
**[[5wzy]] – zeAGC P2X4 + CTP<br />
* Proton channel or matrix protein 2
* Proton channel or matrix protein 2
Line 222: Line 341:
**[[2kih]], [[2kwx]] – IVproton channel (mutant)<br />
**[[2kih]], [[2kwx]] – IVproton channel (mutant)<br />
**[[3bkd]], [[4qkm]], [[4qkl]], [[4qkc]], [[4qk7]], [[3lbw]], [[5ttc]], [[5um1]], [[5joo]] - IVproton channel transmembrane domain<br />
**[[3bkd]], [[4qkm]], [[4qkl]], [[4qkc]], [[4qk7]], [[3lbw]], [[5ttc]], [[5um1]], [[5joo]] - IVproton channel transmembrane domain<br />
-
**[[1nyj]], [[1mp6]], [[2kad]] - IVproton channel transmembrane domain - NMR<br />
+
**[[1nyj]], [[1mp6]], [[2kad]], [[6pvr]], [[6pvt]] - IVproton channel transmembrane domain - NMR<br />
-
**[[5c02]], [[4rwc]], [[4rwb]], [[2kih]] - IVproton channel transmembrane domain (mutant)<br />
+
**[[5c02]], [[4rwc]], [[4rwb]], [[2kih]], [[6mjh]] - IVproton channel transmembrane domain (mutant)<br />
**[[2n70]] - IVproton channel transmembrane domain (mutant) - NMR<br />
**[[2n70]] - IVproton channel transmembrane domain (mutant) - NMR<br />
-
**[[6bkk]], [[6bkl]], [[6bmz]], [[6boc]] - IVproton channel transmembrane domain + drug<br />
+
**[[6bkk]], [[6bkl]], [[6bmz]], [[6boc]], [[6us8]], [[6us9]] - IVproton channel transmembrane domain + drug<br />
-
**[[2kqt]] - IVproton channel transmembrane domain + drug - NMR<br />
+
**[[2h95]], [[2kqt]] - IVproton channel transmembrane domain + drug - NMR<br />
**[[2ly0]] - IVproton channel transmembrane domain (mutant) + drug - NMR<br />
**[[2ly0]] - IVproton channel transmembrane domain (mutant) + drug - NMR<br />
**[[2rlf]] - IVproton channel + inhibitor - NMR<br />
**[[2rlf]] - IVproton channel + inhibitor - NMR<br />
-
**[[3c9j]] - IVproton channel transmembrane domain + inhibitor<br />
+
**[[3c9j]], [[6oug]] - IVproton channel transmembrane domain + inhibitor<br />
 +
**[[6nv1]] - IVproton channel transmembrane domain (mutant) + inhibitor<br />
 +
**[[8bdz]], [[8ber]] - proton channel M2 – Hepatitis virus – Cryo EM<br />
* Voltage-gated hydrogen channel (VGHC)
* Voltage-gated hydrogen channel (VGHC)
Line 238: Line 359:
**[[3vmx]], [[3vmy]], [[3vmz]] – mVGHC C-terminal<br />
**[[3vmx]], [[3vmy]], [[3vmz]] – mVGHC C-terminal<br />
**[[3vn0]], [[3vyi]] – mVGHC C-terminal (mutant)<br />
**[[3vn0]], [[3vyi]] – mVGHC C-terminal (mutant)<br />
 +
 +
*'''Transient receptor potential cation channel, vanilloid subfamily (TRPV)'''
 +
 +
*''TRPV1 or capsaicin receptor''
 +
 +
**[[7lp9]], [[7lpa]], [[7lpc]], [[7lpd]], [[8gf8]], [[8gf9]], [[8gfa]] – hTRPV1 – Cryo EM<br />
 +
**[[6l93]] – hTRPV1 ankyrin repeat domain 101-365<br />
 +
**[[2nyj]] – hTRPV1 ankyrin repeat domain + ATP<br />
 +
**[[7lqy]], [[7lqz]] – sTRPV1 – squirrel - Cryo EM<br />
 +
**[[7lr0]] – sTRPV1 + capsaicin - Cryo EM<br />
 +
**[[3j5p]], [[3j5r]], [[3j9j]], [[5irz]] – rTRPV1 – Cryo EM<br />
 +
**[[5is0]] – rTRPV1+ capsaicin derivative – Cryo EM<br />
 +
**[[5irx]] – rTRPV1+ DKTX – Cryo EM<br />
 +
**[[3j5q]] – rTRPV1+ toxin – Cryo EM<br />
 +
**[[2pnn]] – rTRPV1 ankyrin repeat domain <br />
 +
**[[7l2h]], [[7l2i]], [[7l2j]], [[7l2k]], [[7l2l]], [[7l2m]], [[7l2n]], [[7l2o]], [[7l2p]], [[7l2r]], [[7l2s]], [[7l2t]], [[7l2u]], [[7l2v]], [[7l2w]], [[7l2x]], [[7lpb]], [[7lpe]], [[7mz5]], [[7mz6]], [[7mz7]], [[7mz9]], [[7mza]], [[7mzb]], [[7mzc]], [[7mzd]], [[7mze]], [[7rqu]], [[7rqv]], [[7rqw]], [[7rqx]], [[7rqy]], [[7rqz]] – raTRPV1 + drug – Cryo EM<br />
 +
 +
*''TRPV2''
 +
 +
**[[5hi9]] – hTRPV2 – Cryo EM<br />
 +
**[[2f37]], [[4n5q]] – hTRPV2 ankyrin repeat domain 69-367<br />
 +
**[[2eta]], [[2etb]], [[2etc]] – rTRPV2 ankyrin repeat domain - rat<br />
 +
**[[6bo4]], [[6bo5]], [[6u84]], [[6u86]] – rTRPV2 – Cryo EM<br />
 +
**[[6wkn]], [[7n0m]], [[7n0n]], [[7t37]], [[7t38]], [[7zjh]], [[8slx]], [[8sly]] – raTRPV2 + cannabidiol – Cryo EM<br />
 +
**[[6u88]], [[6u8a]] – rTRPV2 + cannabidiol – Cryo EM<br />
 +
**[[6bwm]] – raTRPV2 – rabbit<br />
 +
**[[5an8]], [[6oo3]], [[6oo4]], [[6oo5]], [[6oo7]] – raTRPV2 – Cryo EM<br />
 +
**[[6bwj]] – raTRPV2 (mutant) + resiniferatoxin<br />
 +
**[[6b5v]] – raTRPV2 + inhibitor – Cryo EM<br />
 +
**[[7xeu]] – mTRPV2 – Cryo EM<br />
 +
**[[7xer]], [[7xew]] – mTRPV2 (mutant) – Cryo EM<br />
 +
**[[7xem]] – mTRPV2 + cholesterol – Cryo EM<br />
 +
**[[7xeo]], [[7xev]], [[7yep]] – mTRPV2 + ligand – Cryo EM<br />
 +
 +
*''TRPV3''
 +
 +
**[[6mho]], [[6mhs]], [[6mhv]], [[6mhw]], [[6mhx]], [[6uw4]] – hTRPV3 – Cryo EM<br />
 +
**[[6ot2]], [[6uw6]], [[6uw8]], [[6uw9]] – hTRPV3 (mutant) – Cryo EM<br />
 +
**[[6ot5]] – hTRPV3 (mutant) + inhibitor – Cryo EM<br />
 +
**[[7xj0]] – hTRPV3 + drug – Cryo EM<br />
 +
**[[6dvw]], [[6dvy]], [[6lgp]], [[6pvl]], [[6pvm]], [[7mik]] – mTRPV3 – Cryo EM<br />
 +
**[[7mij]], [[7mik]], [[7mil]], [[7mim]], [[7min]], [[7mio]], [[7ras]], [[7rau]], [[7ugg]] – mTRPV3 + drug – Cryo EM<br />
 +
**[[6dvz]], [[6pvn]], [[6pvp]], [[6pvo]], [[6pvq]] – mTRPV3 (mutant) – Cryo EM<br />
 +
**[[4n5q]] – mTRPV3 ankyrin repeat domain 118-367<br />
 +
 +
*''TRPV4''
 +
 +
**[[7aa5]] – hTRPV4 + agonist – Cryo EM<br />
 +
**[[4dx1]], [[4dx2]] – hTRPV4 ankyrin repeat domain 149-397<br />
 +
**[[6c8f]], [[6c8g]], [[6c8h]] – fTRPV4 (mutant) – frog<br />
 +
**[[6bbj]] – fTRPV4 – Cryo EM<br />
 +
**[[3jxi]], [[3jxj]], [[3w9g]] – cTRPV4 ankyrin repeat domain 133-382<br />
 +
**[[3w9f]] – cTRPV4 ankyrin repeat domain + inositol-3-phosphate<br />
 +
 +
*''TRPV5''
 +
 +
**[[5oeo]] – hTRPV5 655-725 + calmodulin – NMR<br />
 +
**[[6dmr]], [[6dmu]], [[6o1n]], [[6o1p]], [[6pbe]], [[6pbf]], [[7t6j]], [[7t6k]], [[7t6l]], [[7t6m]], [[7t6n]], [[7t6o]] – rTRPV5 – Cryo EM<br />
 +
**[[6o1u]], [[7t6p]], [[7t6q]], [[7t6r]] – rTRPV5 (mutant) – Cryo EM<br />
 +
**[[6dmw]], [[6o20]] – raTRPV5 + calmodulin – Cryo EM<br />
 +
 +
*''TRPV6''
 +
 +
**[[6bo8]], [[6bo9]], [[7k4a]], [[8fob]] – hTRPV6 – Cryo EM<br />
 +
**[[6boa]], [[6d7s]], [[6d7t]] – hTRPV6 (mutant) – Cryo EM<br />
 +
**[[7k4b]], [[7k4c]], [[7k4d]], [[7k4e]], [[7k4f]], [[7s8c]], [[8foa]] – hTRPV6 + inhibitor – Cryo EM<br />
 +
**[[7s88]], [[7s89]], [[7s8b]] – hTRPV6 + blocker – Cryo EM<br />
 +
**[[5iwk]], [[5iwp]], [[5iwr]], [[5iwt]], [[5wo6]], [[5wo7]], [[5wo8]], [[5wo9]], [[5woa]], [[6d7o]], [[6d7v]] – rTRPV6<br />
 +
**[[6d7p]], [[6d7q]], [[6d7x]] – rTRPV6 (mutant) <br />
 +
**[[6bob]] – rTRPV6 – Cryo EM<br />
 +
**[[6e2f]], [[6e2g]] – rTRPV6 + calmodulin – Cryo EM<br />
 +
**[[2rfa]] – mTRPV6 ankyrin repeat domain 44-265<br />
 +
**[[7d2k]] – raTRPV6 + inhibitor – Cryo EM<br />
*Glycerol facilitator
*Glycerol facilitator

Current revision

3D structures of ion channels

Updated on 05-May-2024


3emn, 4c69 – mVDAC1

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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