Kallikrein 3D structures

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Current revision (08:00, 15 October 2025) (edit) (undo)
 
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Line 6: Line 6:
*Kallikrein 1
*Kallikrein 1
 +
**[[8ygy]] – hKLK - human <br />
**[[1gvz]] – KLK - horse <br />
**[[1gvz]] – KLK - horse <br />
**[[2pka]] – pKLK - pig <br />
**[[2pka]] – pKLK - pig <br />
Line 13: Line 14:
*Kallikrein 2
*Kallikrein 2
-
**[[4nfe]] – hKLK + inhibitor - human <br />
+
**[[4nfe]] – hKLK + inhibitor <br />
**[[4nff]] – hKLK + PPACK <br />
**[[4nff]] – hKLK + PPACK <br />
Line 32: Line 33:
**[[2psy]] – hKLK catalytic domain + leupeptin + Zn<br />
**[[2psy]] – hKLK catalytic domain + leupeptin + Zn<br />
**[[6qfe]] – hKLK + inhibitor <br />
**[[6qfe]] – hKLK + inhibitor <br />
 +
**[[7u5b]] – hKLK + antibody<br />
*Kallikrein 6
*Kallikrein 6
**[[1gvl]] – hKLK (mutant) <br />
**[[1gvl]] – hKLK (mutant) <br />
-
**[[1l2e]], [[1lo6]] – hKLK + inhibitor <br />
+
**[[1l2e]], [[1lo6]], [[7qfv]], [[7qft]], [[7qhz]], [[7qi0]] – hKLK + inhibitor <br />
**[[3vfe]], [[4d8n]], [[6qff]], [[6qfg]], [[6qfh]], [[6qf9]], [[6qfa]], [[6qfb]], [[6qfc]], [[6qh9]], [[6qha]], [[6qhb]], [[6qhc]], [[6skb]], [[6skc]], [[6skd]] – hKLK (mutant) + inhibitor <br />
**[[3vfe]], [[4d8n]], [[6qff]], [[6qfg]], [[6qfh]], [[6qf9]], [[6qfa]], [[6qfb]], [[6qfc]], [[6qh9]], [[6qha]], [[6qhb]], [[6qhc]], [[6skb]], [[6skc]], [[6skd]] – hKLK (mutant) + inhibitor <br />
**[[5nx1]], [[5nx3]] – hKLK + amyloid-b A4 protein<br />
**[[5nx1]], [[5nx3]] – hKLK + amyloid-b A4 protein<br />
Line 62: Line 64:
**[[1ao5]] – KLK - mouse<br />
**[[1ao5]] – KLK - mouse<br />
-
*Plasma kallikrein
+
*Plasma kallikrein; domains – light chain or protease 391-627; heavy chain 20-378
-
**[[6o1g]], [[6i44]], [[6o1s]] – hKLK + inhibitor<br />
+
**[[6i44]] – hKLK + inhibitor<br />
-
**[[7n7x]] – hKLK light chain + inhibitor<br />
+
**[[6o1g]], [[6t7p]], [[7n7x]], [[8a3q]] – hKLK light chain domain + inhibitor<br />
-
**[[4ogx]], [[4ogy]] – hKLK light chain (mutant) + antibody <br />
+
-
**[[5f8z]] – hKLK light chain (mutant) + Pkalin-1 <br />
+
-
**[[5f8t]] – hKLK light chain (mutant) + Pkalin-2 <br />
+
-
**[[5f8x]] – hKLK light chain (mutant) + Pkalin-3 <br />
+
**[[5tjx]], [[2anw]], [[2any]], [[6o1s]] – hKLK light chain (mutant) + inhibitor <br />
**[[5tjx]], [[2anw]], [[2any]], [[6o1s]] – hKLK light chain (mutant) + inhibitor <br />
-
**[[6t7p]] – hKLK protease domain 391-632 + inhibitor<br />
+
**[[8fgx]] – hKLK light chain domain + antibody – Cryo EM<br />
 +
**[[4ogx]], [[4ogy]] – hKLK light chain domain (mutant) + antibody <br />
 +
**[[5f8z]] – hKLK light chain domain (mutant) + Pkalin-1 <br />
 +
**[[5f8t]] – hKLK light chain domain (mutant) + Pkalin-2 <br />
 +
**[[5f8x]] – hKLK light chain domain (mutant) + Pkalin-3 <br />
 +
**[[7qox]] – hKLK heavy chain domain + kininogen-1<br />
 +
**[[9vwt]] – hKLK protease domain + peptide inhibitor<br />
**[[5gvt]] – mKLK protease domain (mutant) <br />
**[[5gvt]] – mKLK protease domain (mutant) <br />
**[[6a8o]] – mKLK protease domain + inhibitor<br />
**[[6a8o]] – mKLK protease domain + inhibitor<br />

Current revision

3D Structures of kallikrein

Updated on 15-October-2025

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky

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