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Activators

From Proteopedia

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(New page: <StructureSection load='4xyk' size='340' side='right' caption='' scene=''> This is a default text for your page '''Activators'''. Click above on '''edit this page''' to modify. Be careful ...)
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<StructureSection load='4xyk' size='340' side='right' caption='' scene=''>
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<StructureSection load='' scene='Phosphofructokinase_(PFK)/4pfk_biol/3' size='350'
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This is a default text for your page '''Activators'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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caption='PFK: R-state Biological tetramer complex with fructose-6-phosphate, ADP and Mg+2 ion; generated from [[4pfk]] by QPS' >
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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Enzyme activators are molecules that bind to enzymes and increase their activity.
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*An example of an enzyme activator working in this way is fructose 2,6-bisphosphate, which activates [[Phosphofructokinase (PFK)|phosphofructokinase 1]] and increases the rate of [[Glycolysis Enzymes|glycolysis]] in response to the hormone [[glucagon]].
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== Function ==
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*[[Hexokinase]]-I (HK-I) is an enzyme activator because it draws glucose into the [[Glycolysis Enzymes|glycolysis]] pathway. Its function is to phosphorylate glucose releasing glucose-6-phosphate (G6P) as the product. HK-I not only signals the activation of glucose into glycolysis but also maintains a low glucose concentration to facilitate glucose diffusion into the cell.
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== Disease ==
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== Relevance ==
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== Structural highlights ==
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>

Current revision

PFK: R-state Biological tetramer complex with fructose-6-phosphate, ADP and Mg+2 ion; generated from 4pfk by QPS

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References

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky

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