1yo7

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Current revision (13:03, 26 July 2023) (edit) (undo)
 
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<StructureSection load='1yo7' size='340' side='right'caption='[[1yo7]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1yo7' size='340' side='right'caption='[[1yo7]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1yo7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YO7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1yo7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YO7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1rop|1rop]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rop ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yo7 OCA], [https://pdbe.org/1yo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yo7 RCSB], [https://www.ebi.ac.uk/pdbsum/1yo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yo7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yo7 OCA], [https://pdbe.org/1yo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yo7 RCSB], [https://www.ebi.ac.uk/pdbsum/1yo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yo7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX]] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.
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[https://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Emery, S C]]
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[[Category: Emery SC]]
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[[Category: Sagermann, M]]
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[[Category: Sagermann M]]
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[[Category: Sander, C]]
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[[Category: Sander C]]
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[[Category: Four-helix bundle]]
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[[Category: Protein design]]
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[[Category: Re-engineering of topology]]
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[[Category: Replication regulator]]
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Current revision

Re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle

PDB ID 1yo7

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