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7q1d

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(New page: '''Unreleased structure''' The entry 7q1d is ON HOLD Authors: Pontillo, N., Guskov, A. Description: Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B [[Category: Unrel...)
Current revision (13:12, 1 February 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7q1d is ON HOLD
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==Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B==
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<StructureSection load='7q1d' size='340' side='right'caption='[[7q1d]], [[Resolution|resolution]] 1.43&Aring;' scene=''>
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Authors: Pontillo, N., Guskov, A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7q1d]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Q1D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Q1D FirstGlance]. <br>
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Description: Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.43&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8I8:[[(2~{R},3~{S})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(3~{R})-4-[[(3~{S})-3-[2-[(1~{S})-1-[[(1~{S},2~{R},3~{R},4~{S},5~{R})-5-azanyl-3-[(4~{S},5~{R})-4-[(2~{S},3~{R},4~{R},5~{S},6~{E})-3-azanyl-6-(azanylmethylidene)-4,5-bis(oxidanyl)oxan-2-yl]oxy-5-(hydroxymethyl)-3-oxidanyl-oxolan-2-yl]oxy-2-[(2~{S},3~{R},4~{R},5~{S})-3-azanyl-6-(iminomethyl)-4,5-bis(oxidanyl)oxan-2-yl]oxy-4-oxidanyl-cyclohexyl]amino]-1-oxidanyl-ethyl]sulfanylethylamino]-3-oxidanyl-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl]+hydrogen+phosphate'>8I8</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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[[Category: Guskov, A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q1d OCA], [https://pdbe.org/7q1d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q1d RCSB], [https://www.ebi.ac.uk/pdbsum/7q1d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q1d ProSAT]</span></td></tr>
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[[Category: Pontillo, N]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AACC3_PSEAI AACC3_PSEAI] Resistance to antibiotics containing the 2-deoxy-streptamine ring including dibekacin, gentamicin, kanamycin, sisomicin, tobramycin, neomycin and to a lesser extent netilmicin.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Guskov A]]
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[[Category: Pontillo N]]

Current revision

Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B

PDB ID 7q1d

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