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1xb9

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Current revision (06:43, 23 August 2023) (edit) (undo)
 
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<StructureSection load='1xb9' size='340' side='right'caption='[[1xb9]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='1xb9' size='340' side='right'caption='[[1xb9]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1xb9]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XB9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1xb9]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XB9 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1k5j|1k5j]], [[1nlq|1nlq]], [[1xe0|1xe0]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xb9 OCA], [https://pdbe.org/1xb9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xb9 RCSB], [https://www.ebi.ac.uk/pdbsum/1xb9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xb9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xb9 OCA], [https://pdbe.org/1xb9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xb9 RCSB], [https://www.ebi.ac.uk/pdbsum/1xb9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xb9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/NPM_XENLA NPM_XENLA]] Acts as a chaperonin for the core histones H3, H2B and H4. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. It may function in the assembly and/or transport of ribosome. May stimulate endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA. May inhibit endonuclease activity on AP single-stranded RNA (By similarity).
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[https://www.uniprot.org/uniprot/NPM_XENLA NPM_XENLA] Acts as a chaperonin for the core histones H3, H2B and H4. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. It may function in the assembly and/or transport of ribosome. May stimulate endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA. May inhibit endonuclease activity on AP single-stranded RNA (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: African clawed frog]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Akey, C W]]
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[[Category: Xenopus laevis]]
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[[Category: Akey, I V]]
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[[Category: Akey CW]]
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[[Category: Head, J F]]
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[[Category: Akey IV]]
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[[Category: Namboodiri, V M]]
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[[Category: Head JF]]
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[[Category: Schmidt-Zachmann, M S]]
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[[Category: Namboodiri VM]]
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[[Category: Chaperone]]
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[[Category: Schmidt-Zachmann MS]]
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[[Category: Histone binding]]
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[[Category: No38]]
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Current revision

The structure and function of Xenopus NO38-core, a histone chaperone in the nucleolus

PDB ID 1xb9

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