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1xbu

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Current revision (14:04, 9 May 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1xbu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XBU FirstGlance]. <br>
<table><tr><td colspan='2'>[[1xbu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XBU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IOY:P-IODO-D-PHENYLALANINE'>IOY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xjo|1xjo]], [[1cp7|1cp7]], [[1qq9|1qq9]], [[1f2p|1f2p]], [[1f2o|1f2o]], [[1tf8|1tf8]], [[1tf9|1tf9]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IOY:P-IODO-D-PHENYLALANINE'>IOY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xbu OCA], [https://pdbe.org/1xbu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xbu RCSB], [https://www.ebi.ac.uk/pdbsum/1xbu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xbu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xbu OCA], [https://pdbe.org/1xbu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xbu RCSB], [https://www.ebi.ac.uk/pdbsum/1xbu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xbu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/APX_STRGR APX_STRGR]] Specific for larger hydrophobic acids, especially leucine. No cleavage occurs if the next residue is proline.
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[https://www.uniprot.org/uniprot/APX_STRGG APX_STRGG] An exopeptidase specific for larger hydrophobic amino acids (especially leucine), no cleavage occurs if the next residue is proline (PubMed:8444149).<ref>PMID:2503378</ref> <ref>PMID:8444149</ref> <ref>PMID:8665903</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
*[[Streptomyces griseus Aminopeptidase (SGAP)|Streptomyces griseus Aminopeptidase (SGAP)]]
*[[Streptomyces griseus Aminopeptidase (SGAP)|Streptomyces griseus Aminopeptidase (SGAP)]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Streptomyces griseus]]
[[Category: Streptomyces griseus]]
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[[Category: Blumberg, S]]
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[[Category: Blumberg S]]
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[[Category: Gilboa, R]]
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[[Category: Gilboa R]]
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[[Category: Reiland, V]]
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[[Category: Reiland V]]
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[[Category: Schomburg, D]]
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[[Category: Schomburg D]]
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[[Category: Shoham, G]]
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[[Category: Shoham G]]
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[[Category: Shoham, Y]]
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[[Category: Shoham Y]]
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[[Category: Spungin-Bialik, A]]
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[[Category: Spungin-Bialik A]]
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[[Category: Calcium activation]]
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[[Category: Double-zinc metalloproteinase]]
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[[Category: Hydrolase]]
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[[Category: Protein-inhibitor complex]]
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Current revision

Streptomyces griseus aminopeptidase complexed with p-iodo-D-phenylalanine

PDB ID 1xbu

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