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7aqy
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| - | ==== | + | ==Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB11)== |
| - | <StructureSection load='7aqy' size='340' side='right'caption='[[7aqy]]' scene=''> | + | <StructureSection load='7aqy' size='340' side='right'caption='[[7aqy]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7aqy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AQY FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7aqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7aqy OCA], [https://pdbe.org/7aqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7aqy RCSB], [https://www.ebi.ac.uk/pdbsum/7aqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7aqy ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7aqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7aqy OCA], [https://pdbe.org/7aqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7aqy RCSB], [https://www.ebi.ac.uk/pdbsum/7aqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7aqy ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VSM2_TRYBB VSM2_TRYBB] VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Lama glama]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Trypanosoma brucei brucei]] |
| + | [[Category: Hempelmann A]] | ||
| + | [[Category: Stebbins CE]] | ||
| + | [[Category: VanStraaten M]] | ||
Current revision
Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB11)
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