7ohx

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==Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL34 expression shut down, population A==
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<StructureSection load='7ohx' size='340' side='right'caption='[[7ohx]]' scene=''>
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<StructureSection load='7ohx' size='340' side='right'caption='[[7ohx]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7ohx]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OHX FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ohx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ohx OCA], [https://pdbe.org/7ohx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ohx RCSB], [https://www.ebi.ac.uk/pdbsum/7ohx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ohx ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ohx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ohx OCA], [https://pdbe.org/7ohx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ohx RCSB], [https://www.ebi.ac.uk/pdbsum/7ohx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ohx ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MAK16_YEAST MAK16_YEAST] Its role might be as part of the apparatus concerned with the nuclear events of the cell cycle.<ref>PMID:3045810</ref>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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In yeast and human cells many of the ribosomal proteins (r-proteins) are required for the stabilisation and productive processing of rRNA precursors. Functional coupling of r-protein assembly with the stabilisation and maturation of subunit precursors potentially promotes the production of ribosomes with defined composition. To further decipher mechanisms of such an intrinsic quality control pathway we analysed here the contribution of three yeast large ribosomal subunit r-proteins rpL2 (uL2), rpL25 (uL23) and rpL34 (eL34) for intermediate nuclear subunit folding steps. Structure models obtained from single particle cryo-electron microscopy analyses provided evidence for specific and hierarchic effects on the stable positioning and remodelling of large ribosomal subunit domains. Based on these structural and previous biochemical data we discuss possible mechanisms of r-protein dependent hierarchic domain arrangement and the resulting impact on the stability of misassembled subunits.
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Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.,Poll G, Pilsl M, Griesenbeck J, Tschochner H, Milkereit P PLoS One. 2021 Nov 23;16(11):e0252497. doi: 10.1371/journal.pone.0252497. , eCollection 2021. PMID:34813592<ref>PMID:34813592</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 7ohx" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
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*[[Ribosome 3D structures|Ribosome 3D structures]]
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*[[Ribosome biogenesis protein 3D structures|Ribosome biogenesis protein 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Milkereit P]]
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[[Category: Poell G]]

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Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL34 expression shut down, population A

PDB ID 7ohx

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